Department of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY, 10065, USA.
Samuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
BMC Med Res Methodol. 2020 May 7;20(1):105. doi: 10.1186/s12874-020-00999-9.
The objective of this study was to assess the overall quality of study-level meta-analyses in high-ranking journals using commonly employed guidelines and standards for systematic reviews and meta-analyses.
100 randomly selected study-level meta-analyses published in ten highest-ranking clinical journals in 2016-2017 were evaluated by medical librarians against 4 assessments using a scale of 0-100: the Peer Review of Electronic Search Strategies (PRESS), Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), Institute of Medicine's (IOM) Standards for Systematic Reviews, and quality items from the Cochrane Handbook. Multiple regression was performed to assess meta-analyses characteristics' associated with quality scores.
The overall median (interquartile range) scores were: PRESS 62.5(45.8-75.0), PRISMA 92.6(88.9-96.3), IOM 81.3(76.6-85.9), and Cochrane 66.7(50.0-83.3). Involvement of librarians was associated with higher PRESS and IOM scores on multiple regression. Compliance with journal guidelines was associated with higher PRISMA and IOM scores.
This study raises concerns regarding the reporting and methodological quality of published MAs in high impact journals Early involvement of information specialists, stipulation of detailed author guidelines, and strict adherence to them may improve quality of published meta-analyses.
本研究旨在使用系统评价和荟萃分析的常用指南和标准，评估高排名期刊中研究水平荟萃分析的整体质量。
由医学图书馆员使用 0-100 分的评分标准，对 2016-2017 年在十本最高排名的临床期刊上发表的 100 篇随机选择的研究水平荟萃分析进行评估，评估标准有四项：电子检索策略同行评审（PRESS）、系统评价和荟萃分析的首选报告项目（PRISMA）、医学研究所（IOM）系统评价标准，以及 Cochrane 手册中的质量项目。进行多元回归分析，以评估荟萃分析特征与质量评分的关系。
总体中位数（四分位距）评分为：PRESS 为 62.5（45.8-75.0），PRISMA 为 92.6（88.9-96.3），IOM 为 81.3（76.6-85.9），Cochrane 为 66.7（50.0-83.3）。图书馆员的参与与 PRESS 和 IOM 评分较高有关。期刊指南的遵循与 PRISMA 和 IOM 评分较高有关。
本研究对高影响力期刊中发表的 MA 的报告和方法学质量提出了关注。早期信息专家的参与、详细的作者指南的规定和严格遵守这些指南可能会提高发表的荟萃分析的质量。
