Department of Surgery Western Health, The University of Melbourne, Melbourne, Victoria, Australia
Nutrition and Dietetics, Western Health, Footscray, Victoria, Australia.
BMJ Open. 2020 May 7;10(5):e035824. doi: 10.1136/bmjopen-2019-035824.
Nutritional intervention and prevention of malnutrition is significantly important for patients with upper gastrointestinal oesophageal, pancreatic and gastric cancer. However, there is limited information regarding nutritional status, and perioperative nutritional interventions that patients receive when undergoing curative surgery.
Patients diagnosed with upper gastrointestinal cancer, planned for curative intent resection across 27 Australian hospitals will be eligible to participate in this point prevalence study. The primary aim is to determine the prevalence of malnutrition in patients with upper gastrointestinal cancer at the time of surgery using subjective global assessment. Secondary aims are to determine the type and frequency of perioperative nutritional intervention received, the prevalence of clinically important weight loss and low muscle strength, and to investigate associations between the use of an evidence-based nutrition care pathway or protocol for the nutritional management of upper gastrointestinal surgical oncology patients and malnutrition prevalence. Data collection will be completed using a purpose-built data collection tool.
Ethical approval was granted in May 2019 (LNR/51107/PMCC-2019). The design and reporting of this study comply with the Strengthening the Reporting of Observational Studies in Epidemiology checklist for reporting of observational cohort studies. Findings will be published in peer-reviewed scholarly journals and presented at relevant conferences. Results will assist in defining priority areas for research to improve patient outcomes.
营养干预和预防营养不良对上消化道食管癌、胰腺癌和胃癌患者非常重要。然而,对于接受根治性手术的患者的营养状况和围手术期营养干预,相关信息有限。
在澳大利亚 27 家医院诊断为上消化道癌症并计划接受根治性切除的患者将有资格参加这项现况研究。主要目的是使用主观整体评估法确定手术时上消化道癌症患者的营养不良患病率。次要目的是确定围手术期接受的营养干预的类型和频率、临床上显著的体重减轻和低肌肉强度的患病率,并调查上消化道肿瘤外科患者营养管理的循证营养护理途径或方案的使用与营养不良患病率之间的关联。将使用专门设计的数据收集工具完成数据收集。
2019 年 5 月获得了伦理批准(LNR/51107/PMCC-2019)。本研究的设计和报告符合观察性队列研究报告的加强观察性研究报告的流行病学清单标准。研究结果将发表在同行评议的学术期刊上,并在相关会议上展示。研究结果将有助于确定改善患者预后的研究优先领域。