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2019年冠状病毒病在儿童中的胸部CT表现及临床特征

Chest CT findings and clinical features of coronavirus disease 2019 in children.

作者信息

Zhong Zheng, Xie Xingzhi, Huang Wei, Zhao Wei, Yu Qizhi, Liu Jun

机构信息

Department of Radiology, First Hospital of Changsha, Changsha 410005

Changsha Public Health Treatment Center, Changsha 410153

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Mar 28;45(3):236-242. doi: 10.11817/j.issn.1672-7347.2020.200206.

Abstract

OBJECTIVES

To describe the CT features and clinical characteristics of pediatric patients with coronavirus disease 2019 (COVID-19).

METHODS

A total of 9 COVID-19 infected pediatric patients were included in this study. Clinical history, laboratory examination, and detailed CT imaging features were analyzed. All patients underwent the first CT scanning on the same day of being diagnosed by real-time reverse-transcription polymerase chain reaction (rRT-PCR). A low-dose CT scan was performed during follow-up.

RESULTS

All the child patients had positive results. Four patients had cough and one patient had fever. One patient presented both cough and fever. Two children presented other symptoms like sore throat and stuffy nose. One child showed no clinical symptom. Five patients had positive initial CT findings with subtle lesions like ground-glass opacity (GGO) or spot-like mixed consolidation. Three patients were reported with negative results in the initial and follow-up CT examination. One patient was reported with initial negative CT findings but turning positive during the first follow-up. All patients had absorbed lesions on follow-up CT images after treatment.

CONCLUSIONS

Pediatric COVID-19 patients have certain imaging and clinical features as well as disease prognosis. Children with COVID-19 tend to have normal or subtle CT findings and relatively better outcome.

摘要

目的

描述2019冠状病毒病(COVID-19)患儿的CT特征及临床特点。

方法

本研究共纳入9例COVID-19感染患儿。分析其临床病史、实验室检查及详细的CT影像特征。所有患者在通过实时逆转录聚合酶链反应(rRT-PCR)确诊的同一天进行首次CT扫描。随访期间进行低剂量CT扫描。

结果

所有患儿检测结果均为阳性。4例患儿有咳嗽症状,1例患儿有发热症状。1例患儿同时出现咳嗽和发热症状。2例患儿出现如咽痛、鼻塞等其他症状。1例患儿无临床症状。5例患儿初始CT检查结果为阳性,表现为磨玻璃影(GGO)或斑片状混合实变等轻微病变。3例患儿初始及随访CT检查结果为阴性。1例患儿初始CT检查结果为阴性,但在首次随访时转为阳性。所有患者经治疗后随访CT图像上病变均吸收。

结论

儿童COVID-19患者具有一定的影像学和临床特征以及疾病预后情况。COVID-19患儿的CT表现往往正常或轻微,预后相对较好。

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