Nie Wei, Feng Zhichao, Mao Xiaowen, Rong Pengfei, Wang Wei, Liang Qi
Department of Radiology, Third Xiangya Hospital, Central South University, Changsha 410013
Department of Radiology, Third Xiangya Hospital, Central South University, Changsha 410013.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Mar 28;45(3):262-268. doi: 10.11817/j.issn.1672-7347.2020.200136.
To investigate imaging features of the coronavirus disease 2019 (COVID-19), and to provide concrete evidences for diagnosis of COVID-19.
Imaging data of the first chest CT examination and clinical data (age, sex, clinical history, epidemiological history, and laboratory tests) of 163 patients with COVID-19 from 2 hospitals were collected for retrospective analysis. Imaging features of the first chest CT examination and the correspondence between CT manifestations and the nucleic acid test results of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were analyzed.
The first chest CT images of 163 COVID-19 patients showed that 92.02% of lesions were ground-glass opacity (GGO), 76.69% were consolidation, and 73.62% were GGO together with consolidation. Multiple lesions were found in 71.17% patients and multiple lobules in 86.50% patients. Lesions in 53.37% patients were found with bronchial inflation signs and those in 36.20% patients presented with "crazy paving" pattern, while only 7.36% were found with hilar node enlargement and pleural effusion. First CT findings of 18 patients were found to be inconsistent with the results of pathogen examination.
COVID-19 patients showed specific features in the first chest CT examination. The combination of the first chest CT imaging features and SARS-CoV-2 nucleic acid test results as well as reexamination if necessary can help to make the diagnosis of SARS-CoV-2 infection accurately.
探讨2019冠状病毒病（COVID-19）的影像学特征，为COVID-19的诊断提供具体依据。
收集两家医院163例COVID-19患者首次胸部CT检查的影像资料及临床资料（年龄、性别、临床病史、流行病学史和实验室检查结果）进行回顾性分析。分析首次胸部CT检查的影像学特征以及CT表现与严重急性呼吸综合征冠状病毒2（SARS-CoV-2）核酸检测结果的相关性。
163例COVID-19患者的首次胸部CT图像显示，92.02%的病灶为磨玻璃影（GGO），76.69%为实变影，73.62%为GGO合并实变影。71.17%的患者有多发病灶，86.50%的患者有多个肺小叶受累。53.37%的患者病灶有支气管充气征，36.20%的患者呈“铺路石”样表现，仅有7.36%的患者有肺门淋巴结肿大及胸腔积液。18例患者的首次CT表现与病原体检查结果不一致。
COVID-19患者首次胸部CT检查具有特征性表现。结合首次胸部CT影像学特征、SARS-CoV-2核酸检测结果以及必要时的复查有助于准确诊断SARS-CoV-2感染。
