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滑石粉所致肺部疾病的支气管肺泡灌洗术

Bronchoalveolar lavage in talc induced lung disease.

作者信息

Redondo A A, Ettensohn D B, Khan M, Kessimian N

机构信息

Department of Medicine, Memorial Hospital of Rhode Island, Pawtucket.

出版信息

Thorax. 1988 Dec;43(12):1019-21. doi: 10.1136/thx.43.12.1019.

DOI:10.1136/thx.43.12.1019
PMID:3238633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC461626/
Abstract

A 65 year old woman with a history of occupational talc inhalation presented with hypoxaemia, cough, and dyspnoea with a normal chest radiograph. Bronchoalveolar lavage showed considerable lymphocytosis, with a predominance of T8+ T lymphocytes, and open lung biopsy showed peribronchiolar granulomas containing talc crystals. Corticosteroid treatment resulted in dramatic improvement. Bronchoalveolar lavage may aid in the diagnosis of talc related lung injury.

摘要

一名有职业性滑石粉吸入史的65岁女性,出现低氧血症、咳嗽和呼吸困难,胸部X线片正常。支气管肺泡灌洗显示淋巴细胞显著增多,以T8+ T淋巴细胞为主,开胸肺活检显示含有滑石粉晶体的支气管周围肉芽肿。皮质类固醇治疗取得显著改善。支气管肺泡灌洗可能有助于滑石粉相关肺损伤的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2d0/461626/ca082440154f/thorax00276-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2d0/461626/ca082440154f/thorax00276-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2d0/461626/ca082440154f/thorax00276-0074-a.jpg

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Bronchoalveolar lavage in talc induced lung disease.滑石粉所致肺部疾病的支气管肺泡灌洗术
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本文引用的文献

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EFFECT OF TALE DUST INHALATION ON LUNG FUNCTION.
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Talc granulomatosis: laboratory findings similar to sarcoidosis.滑石肉芽肿病:实验室检查结果与结节病相似。
Am Rev Respir Dis. 1982 Feb;125(2):258-61. doi: 10.1164/arrd.1982.125.2.258.
6
T-lymphocytosis in bronchoalveolar lavage fluid of hypersensitivity pneumonitis. Changes in profile of T-cell subsets during the course of disease.过敏性肺炎支气管肺泡灌洗液中的T淋巴细胞增多症。疾病过程中T细胞亚群谱的变化。
Chest. 1984 Apr;85(4):514-22. doi: 10.1378/chest.85.4.514.
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Life-threatening theophylline toxicity is not predictable by serum levels.
Chest. 1987 Jan;91(1):10-4. doi: 10.1378/chest.91.1.10.