Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark.
Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark.
Cell Stem Cell. 2020 May 7;26(5):609-610. doi: 10.1016/j.stem.2020.04.013.
Johnny Thunders once wrote, "You can't put your arms around a memory…" and the song continues, "don't try." Yet, when complex morphogenetic movements accompany differentiation, the cellular memory of signaling becomes essential. In this issue of Cell Stem Cell, Gunne-Braden et al. (2020) report a network wrapping its arms around the memory of BMP signaling, a phenomenon known as hysteresis.
约翰尼·桑德斯（Johnny Thunders）曾写道：“你无法拥抱回忆……”接着歌曲唱道：“别尝试。”然而，当复杂的形态发生运动伴随着分化时，信号转导的细胞记忆就变得至关重要。在本期《细胞干细胞》杂志中，Gunne-Braden 等人（2020）报道了一个围绕着 BMP 信号转导记忆的网络，这种现象被称为滞后现象。
