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法国五十岁以上骨折患者的真实世界护理:护理差距较大的证据——EPIFRACT 研究。

Real-world care for individuals aged over fifty with fractures in France: Evidence for a wide care gap-The EPIFRACT Study.

机构信息

Service de rhumatologie, hôpital Cochin, Paris, France.

Service de rhumatologie, CHU Grenoble Alpes, Hôpital Sud, Echirolles, France; AFLAR - Association Française de Lutte Anti-Rhumatismale, Paris, France.

出版信息

Joint Bone Spine. 2020 Oct;87(5):467-473. doi: 10.1016/j.jbspin.2020.04.007. Epub 2020 May 5.

Abstract

OBJECTIVES

To describe the care trajectories of adults aged ≥50 years with fragility fractures in France.

METHODS

A postal questionnaire was sent to 15,000 individuals aged ≥50 years extracted from a representative panel of the French population (METASKOPE) in April-May 2018. Respondents experiencing a single fragility fracture in the previous three years constituted the study population. Information was collected regarding diagnosis, hospitalisations, physician visits and treatment related to the fractures.

RESULTS

13,914 participants returned a questionnaire (92.8%), of whom 436 reported a single fragility fracture. Their mean age was 68.7±10.3 years. 11.9% of this sample had undergone bone densitometry (DXA) prior to the fracture and 11.9% had received a diagnostic of osteoporosis. Following the fracture, a further 17.4% underwent DXA and 8.5% were diagnosed with osteoporosis. 74.3% of fractures were initially managed in an emergency department and 29.6% led to immediate hospitalisation. Prior to fracture, 3.4% received a specific anti-osteoporotic treatment, 10.1% vitamin D and 6.4% calcium supplementation. After the fracture, these figures rose to 10.8%, 26.8% and 19.0% respectively. 86.2% participants made at least one follow-up visit to a physician.

CONCLUSIONS

The rate of DXA screening following fragility fractures in subjects over fifty is very low. Most patients with fragility fractures did not receive a diagnosis of osteoporosis. The proportion of patients treated with a specific anti-osteoporotic treatment after a fracture is low even though around half consulted their general practitioner after the fracture. Practice guidelines are thus not being adhered to in everyday clinical practice in France.

摘要

目的

描述法国≥50 岁脆性骨折成年人的护理轨迹。

方法

2018 年 4 月至 5 月,向从法国代表性人群抽样调查(METASKOPE)中抽取的 15000 名≥50 岁的个体邮寄调查问卷。在过去三年中经历过单一脆性骨折的受访者构成了研究人群。收集了与骨折相关的诊断、住院、就诊和治疗信息。

结果

13914 名参与者返回了问卷(92.8%),其中 436 名报告了单一脆性骨折。他们的平均年龄为 68.7±10.3 岁。该样本中有 11.9%在骨折前进行了骨密度(DXA)检查,11.9%被诊断为骨质疏松症。骨折后,又有 17.4%接受了 DXA 检查,8.5%被诊断为骨质疏松症。74.3%的骨折最初在急诊科进行治疗,29.6%导致立即住院。骨折前,3.4%接受了特定的抗骨质疏松治疗,10.1%接受了维生素 D 补充,6.4%接受了钙补充。骨折后,这些数字分别上升至 10.8%、26.8%和 19.0%。86.2%的参与者至少进行了一次随访就诊。

结论

五十多岁人群中,脆性骨折后进行 DXA 筛查的比例非常低。大多数脆性骨折患者未被诊断为骨质疏松症。骨折后接受特定抗骨质疏松治疗的患者比例较低,尽管大约一半的患者在骨折后咨询了他们的全科医生。因此,法国的临床实践并未遵循实践指南。

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