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在原发性髋关节和膝关节化脓性关节炎中,药物治疗与手术治疗的比较。

Medical versus surgical treatment in native hip and knee septic arthritis.

机构信息

Department of Infectious Diseases, University Hospital of Amiens-Picardie, Amiens, France.

Department of Infectious Diseases, University Hospital of Amiens-Picardie, Amiens, France.

出版信息

Infect Dis Now. 2021 Mar;51(2):164-169. doi: 10.1016/j.medmal.2020.04.019. Epub 2020 May 5.

Abstract

OBJECTIVE

Antibiotic treatment and arthroscopic or open drainage is the gold standard for septic arthritis. Full recovery takes time after surgery and hospital stay is longer than for arthrocentesis at the bedside. We aimed to evaluate the effectiveness of arthrocentesis (medical approach) versus a surgical approach.

METHOD

We retrospectively included 97 cases of native joint arthritis (hip and knee) between 2010 and 2017. The primary outcome was treatment failure of medical and surgical approaches (defined as surgical intervention within 7 days following diagnosis). Risk factors of failure were identified by univariable and multivariable logistic regression.

RESULTS

We included 72 cases of knee arthritis, of which 43 and 29 were treated medically and surgically, respectively; 25 cases of hip arthritis, of which 8 and 17 were treated medically and surgically, respectively. Failure was observed in 39.2% of cases in the medical group and in 30.4% in the surgical group (P=0.2) (37.5% vs. 52.9% and 39.5% vs. 17.2% for hip and knee, respectively). The univariate analysis identified age and male sex as risk factors for failure (P=0.048 and P=0.02, respectively), but only age was independently associated with failure (P=0.04). Hospital length of stay was 12 days shorter in the medical group (21 vs. 33 days, P=0.02), sequelae were less frequent and less important in the medical group (31.7% vs. 60%).

CONCLUSION

The medical treatment seems to be as effective as the surgical treatment for native joint septic arthritis with a shorter hospital stay and better functional outcome. Further prospective studies are warranted.

摘要

目的

抗生素治疗和关节镜或切开引流是治疗化脓性关节炎的金标准。手术后完全康复需要时间,住院时间也比床边关节穿刺术长。我们旨在评估关节穿刺术(内科方法)与外科方法的效果。

方法

我们回顾性纳入了 2010 年至 2017 年间的 97 例原发性关节关节炎(髋关节和膝关节)患者。主要结局是内科和外科治疗的失败(定义为在诊断后 7 天内进行手术干预)。通过单变量和多变量逻辑回归识别失败的危险因素。

结果

我们纳入了 72 例膝关节关节炎患者,其中 43 例和 29 例分别接受内科和外科治疗;25 例髋关节关节炎患者,其中 8 例和 17 例分别接受内科和外科治疗。内科组失败率为 39.2%,外科组为 30.4%(P=0.2)(髋关节和膝关节分别为 37.5%比 52.9%和 39.5%比 17.2%)。单变量分析确定年龄和男性为失败的危险因素(P=0.048 和 P=0.02),但只有年龄与失败独立相关(P=0.04)。内科组的住院时间缩短了 12 天(21 天比 33 天,P=0.02),内科组的后遗症较少且较不严重(31.7%比 60%)。

结论

对于原发性关节化脓性关节炎,内科治疗与外科治疗一样有效,且住院时间更短,功能结局更好。需要进一步的前瞻性研究。

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