Ohya K, Morishima Y, Funato E, Hasegawa I, Kamiya T
Aichi Blood Center Japanese Red Cross Society, Japan.
Vox Sang. 1988;55(3):148-51. doi: 10.1111/j.1423-0410.1988.tb05082.x.
A particle agglutination (PA) assay for antibody to human immunodeficiency virus type I (anti-HIV) was used to screen blood donors and to test leukemia and hemophilia patients. Results by PA showed complete agreement with the results of two kinds of enzyme immunoassay (EIA), and the false-positive rate was the same as or lower than with the EIAs. The sensitivity of PA was 10- to 100-fold higher than that of the EIAs. This simple sensitive assay takes less time and fewer personnel than the EIAs, and has been used for massive screening of blood donors in our blood center.
采用一种检测抗人类免疫缺陷病毒I型抗体（抗-HIV）的颗粒凝集（PA）试验来筛查献血者，并检测白血病和血友病患者。PA试验的结果与两种酶免疫测定（EIA）的结果完全一致，且假阳性率与EIA相同或更低。PA试验的灵敏度比EIA高10至100倍。这种简单灵敏的试验比EIA所需时间更少，人员需求也更少，已在我们的血液中心用于大规模筛查献血者。
