Kitagawa Shuji, Watanabe Yusaku, Katada Yousuke, Iwamoto Ryo, Kinoshita Seiya, Ueno Michi, Mineta Shumei, Okamoto Yuko, Kubota Hisako, Higashida Masaharu, Okada Toshimasa, Tsuruta Atsushi, Fujiwara Yoshinori, Yamaguchi Yoshiyuki, Ueno Tomio
Dept. of Gastroenterological Surgery, Kawasaki Medical School.
Gan To Kagaku Ryoho. 2020 Apr;47(4):722-724.
A 68-year-old man presented to our hospital. An upper gastrointestinal tract endoscopy performed elsewhere revealed an elevated lesion with a circumferential esophageal cancer(identified as small cell carcinoma). Perthe treatment forsmall cell cancer and the standard treatment for esophageal neuroendocrine carcinoma, 7 courses of CBDCA(5mg/m2)plus ETP (100mg/m2)were administered. The lesion shrank and the lymph node swelling disappeared and the patient was deemed to be in partial remission. Nine months later, however, the primary tumor increased in size. A transthoracic subtotal esophagectomy( laparoscope-assisted), 2 area dissection, and gastric tube reconstruction(post-sternal)were performed at 2 years and 10 months afterdiagnosis.
一名68岁男性前来我院就诊。在其他地方进行的上消化道内镜检查发现一个隆起性病变,为食管环周癌(确诊为小细胞癌)。按照小细胞癌的治疗方法以及食管神经内分泌癌的标准治疗方案,给予7个疗程的顺铂(5mg/m²)联合依托泊苷(100mg/m²)治疗。病变缩小,淋巴结肿大消失,患者被认为处于部分缓解状态。然而,9个月后,原发肿瘤增大。在诊断后2年10个月时进行了经胸次全食管切除术(腹腔镜辅助)、2区域清扫以及胃管重建(胸骨后)。