Devi Pooja, Aghighi Maryam, Mikhail Nagy
Pathology, Saint Barnabas Medical Center, Robert Wood Johnson Barnabas Health, Livingston, USA.
Pathology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Cureus. 2020 Apr 7;12(4):e7582. doi: 10.7759/cureus.7582.
Struma ovarii is a variant of a germ cell tumor composed predominantly of thyroid tissue. It is most often unilateral. The incidence of malignancy arising in patients with struma ovarii is rare. Here, we present a case of struma ovarii in a female presented with abdominal distension. The patient was treated with a total hysterectomy and bilateral salpingo-oophorectomy, which revealed an enlarged cystically dilated ovary. Histopathologic examination showed mature thyroid follicles with abundant colloid consistent with struma ovarii and focal area with nuclear features of papillary thyroid carcinoma. No other teratomatous elements were identified. Thyroid hormone levels were within their respective reference ranges. A diagnosis of struma ovarii should be considered in the differential diagnosis of pelvic masses in peri- and postmenopausal patients.
卵巢甲状腺肿是一种主要由甲状腺组织构成的生殖细胞肿瘤变体。它大多为单侧性。卵巢甲状腺肿患者发生恶变的情况很罕见。在此，我们报告一例表现为腹胀的女性卵巢甲状腺肿病例。该患者接受了全子宫切除术及双侧输卵管卵巢切除术，术中发现一侧卵巢增大，呈囊状扩张。组织病理学检查显示有成熟的甲状腺滤泡，含丰富胶质，符合卵巢甲状腺肿表现，且有局灶区域具有甲状腺乳头状癌的核特征。未发现其他畸胎瘤成分。甲状腺激素水平在各自的参考范围内。对于围绝经期和绝经后患者盆腔肿块的鉴别诊断，应考虑卵巢甲状腺肿。
