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韩国老年人的跌倒恐惧与死亡率:韩国老年纵向研究分析

Fear of Falling and Mortality among Older Adults in Korea: Analysis of the Korean Longitudinal Study of Aging.

作者信息

Lee Ari, Lee Jungun, Lee Gyumin, Lee Dong Ryul

机构信息

Department of Family Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine, Gunpo, Korea.

出版信息

Korean J Fam Med. 2020 Jul;41(4):243-249. doi: 10.4082/kjfm.18.0128. Epub 2020 May 12.

Abstract

BACKGROUND

The fear of falling (FOF) has been reported in a high percentage of elderly people. An excessive FOF is a major concern among the elderly because it can lead to permanent disability. However, the impact of FOF on mortality has been insufficiently studied. The aim of this study was to investigate the impact of FOF on mortality among the elderly in Korea.

METHODS

This was a prospective study carried out using the database of the Korean Longitudinal Study of Aging, a nationwide study of community-dwelling adults in Korea. Study participants included 3,421 adults, aged 65 years or older, without either severe cognitive impairment (Korean version of Mini-Mental Status Examination ≥10), or previous history of cancer. We used Cox proportional hazards models to investigate the association between FOF and all-cause mortality.

RESULTS

This study included 1,474 men and 1,947 women. Cox regression showed that participants with FOF had an increased risk of mortality (mild: hazard ratio [HR], 1.25; 95% confidence interval [CI], 1.01-1.54; moderate: HR, 1.59; 95% CI, 1.23-2.05) after adjusting for confounding variables. In a subgroup analysis, FOF was still a significant risk factor of mortality for patients with no previous history of falling after adjusting for other risk factors, as in the full model, except for history of falling (HR, 1.65; 95% CI, 1.27-2.13).

CONCLUSION

We found that FOF was a significant risk factor for mortality in the elderly in Korea. Further studies on the effects and mechanism of FOF on mortality are needed.

摘要

背景

据报道,很大比例的老年人存在跌倒恐惧(FOF)。过度的跌倒恐惧是老年人的一个主要担忧,因为它可能导致永久性残疾。然而,跌倒恐惧对死亡率的影响尚未得到充分研究。本研究的目的是调查跌倒恐惧对韩国老年人死亡率的影响。

方法

这是一项前瞻性研究,使用韩国老年纵向研究数据库进行,该研究是对韩国社区居住成年人的全国性研究。研究参与者包括3421名65岁及以上的成年人,他们没有严重认知障碍(韩国版简易精神状态检查表≥10)或癌症病史。我们使用Cox比例风险模型来研究跌倒恐惧与全因死亡率之间的关联。

结果

本研究包括1474名男性和1947名女性。Cox回归显示,在调整混杂变量后,有跌倒恐惧的参与者死亡风险增加(轻度:风险比[HR],1.25;95%置信区间[CI],1.01 - 1.54;中度:HR,1.59;95% CI,1.23 - 2.05)。在亚组分析中,与完整模型一样,在调整其他风险因素后,对于没有跌倒史的患者,跌倒恐惧仍然是死亡率的一个重要风险因素,除了跌倒史(HR,1.65;95% CI,1.27 - 2.13)。

结论

我们发现跌倒恐惧是韩国老年人死亡率的一个重要风险因素。需要进一步研究跌倒恐惧对死亡率的影响及其机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b132/7385298/d830dc97c283/kjfm-18-0128f1.jpg

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