Department of Cardiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Zuhuratbaba Mah, Dr. Tevfik Sağlam Cd No:11, Bakırköy, 34147, Istanbul, Turkey.
J Thromb Thrombolysis. 2020 Jul;50(1):239-241. doi: 10.1007/s11239-020-02132-5.
Coronavirus disease 2019 (COVID-19) is an infectious disease that primarily affects the respiratory system, but it may cause cardiovascular complications such as thromboembolism. Rarely, pulmonary embolism may be encountered in patients with severe COVID-19 infection, especially in intensive care units. An asymptomatic young case of COVID-19 presenting with sudden death due to acute massive pulmonary embolism has not been previously described. We report a 41-year-old woman presented to emergency department with sudden death during physical activity. She had only history of diabetes mellitus and she was asymptomatic until sudden death. CT pulmonary angiography and chest CT scans revealed acute massive embolism and typical imaging findings of COVID-19 pneumonia, respectively. Interestingly, the patient had no symptoms or signs of infection and also had no risk factors for thromboembolism. COVID-19 infection appears to induce venous thromboembolism, especially pulmonary embolism. The case is remarkable in terms of showing how insidious and life-threatening COVID-19 infection can be.
2019 冠状病毒病（COVID-19）是一种主要影响呼吸系统的传染病，但它可能导致心血管并发症，如血栓栓塞。在重症 COVID-19 感染患者中，尤其是在重症监护病房中，很少会遇到肺栓塞。以前没有报道过无症状的 COVID-19 年轻患者因急性大面积肺栓塞突然死亡。我们报告了一例 41 岁女性，在体力活动时突然死亡就诊于急诊。她只有糖尿病病史，直到突然死亡前她一直无症状。CT 肺动脉造影和胸部 CT 扫描分别显示急性大面积栓塞和 COVID-19 肺炎的典型影像学表现。有趣的是，患者没有感染的症状或体征，也没有血栓栓塞的危险因素。COVID-19 感染似乎会诱发静脉血栓栓塞，尤其是肺栓塞。该病例的显著之处在于表明 COVID-19 感染是多么隐匿和危及生命。
