Section of Psychiatry, Department of Biomedicine, Neuroscience, and Advanced Diagnostic (BIND), University of Palermo, Palermo, Italy.
Department of Health Promotion, Mother, and Child Care, Internal Medicine and Medical Specialties, (PROMISE), University of Palermo, Palermo, Italy.
J Clin Psychol. 2020 Oct;76(10):1807-1817. doi: 10.1002/jclp.22971. Epub 2020 May 11.
This randomized controlled trial examined the efficacy of adding a fasting-mimicking diet to a structured psychotherapy protocol for treating depression.
Of 20 patients with depression, 10 were randomly assigned to psychotherapy and dieting (i.e., experimental group) and the other 10 to psychotherapy only (i.e., control group). Patients in both groups received 20 individual sessions of functional therapy along with nutrition consultation. Patients in the control group were instructed to maintain their usual daily diets.
Both treatments were effective in reducing depression as well as increasing self-esteem and quality of life. The experimental group showed improved self-esteem and psychological quality of life as well as a reduction in their mean body mass index, in comparison to the control group.
The study revealed initial evidence of the efficacy of combining psychotherapy with a fasting-mimicking diet to treat depression and its correlates.
本随机对照试验旨在研究在结构化心理治疗方案中添加限时饮食方案对治疗抑郁症的疗效。
20 名抑郁症患者中，10 名被随机分配至心理治疗加限时饮食组（即实验组），另外 10 名被分配至仅接受心理治疗组（即对照组）。两组患者均接受 20 次个体功能治疗和营养咨询。对照组患者被要求保持其日常饮食。
两种治疗均有效降低了抑郁程度，提高了自尊和生活质量。与对照组相比，实验组的自尊和心理健康状况得到改善，平均体重指数也有所下降。
该研究初步证明了将心理治疗与限时饮食相结合治疗抑郁症及其相关症状的疗效。
