Harackiewicz J M, Blair L W, Sansone C, Epstein J A, Stuchell R N
Department of Psychology, Columbia University, New York, NY 10027.
Addict Behav. 1988;13(4):319-30. doi: 10.1016/0306-4603(88)90038-x.
This study evaluated the effectiveness of nicotine chewing gum in smoking cessation, when incorporated into a behaviorally oriented self-help program. One hundred ninety-seven patients were randomly assigned to nicotine gum with a self-help manual, a self-help manual without gum, or a control condition, but received no further treatment from the prescribing physician. At six weeks, the nicotine gum group was superior to both the self-help and control conditions. By one year, many gum patients had relapsed, and the treatment effect was no longer significant. Patients who were able to quit initially were most likely to remain ex-smokers in the self-help condition. The clinical importance of these findings is discussed.
本研究评估了将尼古丁咀嚼胶纳入以行为为导向的自助戒烟计划时，其在戒烟方面的有效性。197名患者被随机分配到接受尼古丁咀嚼胶加自助手册组、仅接受自助手册组或对照组，且开处方的医生不再给予进一步治疗。六周时，尼古丁咀嚼胶组优于自助组和对照组。到一年时，许多使用咀嚼胶的患者复发，治疗效果不再显著。最初能够戒烟的患者在自助条件下最有可能保持戒烟状态。文中讨论了这些研究结果的临床意义。
