Department of Internal Medicine; Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Saudi J Kidney Dis Transpl. 2020 Mar-Apr;31(2):388-394. doi: 10.4103/1319-2442.284013.
Upper gastrointestinal (GI) abnormality is believed to be higher in patients with end-stage renal disease (ESRD) which can make a big trouble for whom undergo kidney transplant. We conducted this study to assess upper GI findings of patients with ESRD. In the present retrospective study we recorded upper GI endoscopy results in hemodialysis patients who were candidate for renal transplantation during a 10-year period. We reviewed files of 1256 patients with a mean age of 37.6 ± 13.4 years. Half of patients (50.6%) had an abnormal endoscopy. Two most common abnormalities were mild gastritis (35.6%) and gastro-esophageal reflux disease (16.7%). GI ulcers were observed in 11% of patients. Duodenal ulcer was the most common ulcer which was seen in 6.8% of patients. Helicobacter pylori was positive in 32.9% of patients and correlated with GI lesions (P = 0.000, r = 0.371). Longer dialysis duration and older patients revealed more upper GI abnormality (P = 0 .032, <0.001). As long as more than half of our patients have at least one upper GI involvement, we recommended that endoscopy must be done as a pretransplantation evaluation for patients without symptoms who have risk factors for ulcers.
上消化道（GI）异常被认为在终末期肾病（ESRD）患者中更为常见，这可能会给接受肾移植的患者带来很大的麻烦。我们进行了这项研究，以评估 ESRD 患者的上消化道发现。在本回顾性研究中，我们记录了在 10 年期间接受肾移植候选者的血液透析患者的上消化道内镜检查结果。我们回顾了 1256 名患者的档案，平均年龄为 37.6 ± 13.4 岁。一半的患者（50.6%）内镜检查异常。两种最常见的异常是轻度胃炎（35.6%）和胃食管反流病（16.7%）。11%的患者观察到 GI 溃疡。十二指肠溃疡是最常见的溃疡，见于 6.8%的患者。32.9%的患者幽门螺杆菌阳性，与 GI 病变相关（P = 0.000，r = 0.371）。透析时间较长和年龄较大的患者表现出更多的上消化道异常（P = 0.032，<0.001）。由于我们的患者中有一半以上至少有一个上消化道受累，我们建议对于没有症状但有溃疡危险因素的患者，在进行移植前评估时必须进行内镜检查。
