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做还是不做?——COVID-19大流行期间癌症手术分诊指南综述

To Do or Not to Do?-A Review of Cancer Surgery Triage Guidelines in COVID-19 Pandemic.

作者信息

Shinde Rajesh S, Naik Mekhala D, Shinde Shital R, Bhandare Manish S, Chaudhari Vikram A, Shrikhande Shailesh V, Dcruz Anil K

机构信息

Department of Surgical Oncology, Gastrointestinal Cancer Surgery, Apollo Hospitals, Navi Mumbai, India.

Department of Surgical Oncology, Gastrointestinal Cancer Surgery, Bombay Hospital Institute of Medical Sciences, Mumbai, India.

出版信息

Indian J Surg Oncol. 2020 Jun;11(2):175-181. doi: 10.1007/s13193-020-01086-7. Epub 2020 May 11.

Abstract

COVID-19 pandemic has emerged as a global health emergency involving more than 200 countries so far. The number of affected population is on rising, so is the mortality. This crisis has overwhelmed the healthcare infrastructures in many affected countries. Due to overall rising cancer incidence and specific concerns, a cohort of cancer patients forms a distinct subset of the population in whom a correct and timely treatment has a huge impact on the outcome. During this period, oncology care is definitely affected owing to many factors like lockdowns, reduced beds and deferral of elective cases to halt the spread of the pandemic. Surgery remains the best line of defence in many solid organ tumours especially in early stage and is potentially curative. China, the source of this pandemic, has taken more than 3 months to enter the post transitional phase of this pandemic. Deferring cancer surgeries for this long period may have a direct impact on the long-term outcomes of cancer patients. Many surgical oncology associations across the globe have come up with triage guidelines for surgical care of cancer patients; however, these are based on expert opinion rather than actual data. Herein, we intend to review these guidelines with respect to the risk of disease progression in cancer patients. In the absence of actual data on cancer surgery care during this pandemic, clinical decisions should be based on careful consideration of disease-related and patient-related factors. While some of the cancer surgeries can be safely delayed for some time, how long we can delay surgeries safely cannot be answered/ explained by any means. Thorough evaluation and discussion by an expert and experienced multidisciplinary team appears to be the most effective way forward.

摘要

截至目前,新冠疫情已演变成一场涉及200多个国家的全球卫生紧急事件。受影响人口数量在不断上升,死亡率也在上升。这场危机使许多受影响国家的医疗基础设施不堪重负。由于癌症总体发病率上升以及一些特殊问题,癌症患者群体构成了一个独特的人群子集,对他们进行正确及时的治疗对治疗结果有巨大影响。在此期间,由于封锁、床位减少以及推迟择期手术以阻止疫情传播等诸多因素,肿瘤护理肯定受到了影响。手术仍然是许多实体器官肿瘤尤其是早期肿瘤的最佳防御手段,并且有可能治愈。作为疫情发源地的中国,花了三个多月时间进入疫情的后过渡阶段。长时间推迟癌症手术可能会对癌症患者的长期治疗结果产生直接影响。全球许多外科肿瘤协会都出台了癌症患者手术护理的分诊指南;然而,这些指南是基于专家意见而非实际数据。在此,我们打算就癌症患者疾病进展风险对这些指南进行综述。在缺乏疫情期间癌症手术护理实际数据的情况下,临床决策应基于对疾病相关因素和患者相关因素的仔细考虑。虽然一些癌症手术可以安全地推迟一段时间,但我们能安全推迟手术的时长却无法以任何方式给出答案或作出解释。由经验丰富的专家多学科团队进行全面评估和讨论似乎是最有效的前进方式。

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