Miller Scientific, Johnson City, Tennessee.
Department of Urology, Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, New York.
J Urol. 2020 Nov;204(5):1019-1026. doi: 10.1097/JU.0000000000001132. Epub 2020 May 12.
The surgical reintervention rate after prostatic urethral lift is not well characterized but has been estimated at 2% to 3% per year. We performed a systematic review and meta-analysis to determine the surgical reintervention rate after prostatic urethral lift.
We systematically searched MEDLINE®, Embase® and the Cochrane Central Register of Controlled Trials for studies of men treated with prostatic urethral lift reporting at least 1 year of maximum followup data. We performed a random effects meta-analysis to estimate the annual rate of surgical reintervention after prostatic urethral lift, including those performed for lower urinary tract symptoms or involving device explant, additions or replacement. The robustness of the meta-analysis conclusions was evaluated in a one-study removed analysis and heterogeneity was investigated with a subgroup analysis.
In 11 studies (2,016 patients) 153 surgical reinterventions were performed, among which transurethral resection of the prostate/laser (51.0%), repeat prostatic urethral lift (32.7%) and device explant (19.6%) were most common. The annual rate of surgical reintervention was 6.0% per year (95% CI 3.0-8.9). These results were not significantly influenced by any single study. The annual rate of surgical intervention was significantly influenced by the mean duration of patient followup. Surgical reintervention rates were 4.3% per year in studies with 1 year or less mean followup, 10.7% per year in studies with more than 1 year to 3 years mean followup and 5.8% per year in a single study with more than 3 years mean followup (p=0.04).
The surgical reintervention rate with prostatic urethral lift is 6.0% per year and is higher in studies with longer followup durations.
前列腺尿道 lifts 术后再次手术的比率尚未得到很好的描述，但估计每年为 2%至 3%。我们进行了系统的审查和荟萃分析，以确定前列腺尿道 lifts 术后再次手术的比率。
我们系统地检索了 MEDLINE、Embase 和 Cochrane 对照试验中心注册处，以寻找至少有 1 年最大随访数据的接受前列腺尿道 lifts 治疗的男性的研究。我们进行了随机效应荟萃分析，以估计前列腺尿道 lifts 术后每年再次手术的比率，包括因下尿路症状或涉及器械去除、添加或更换而进行的手术。通过一项研究去除分析评估荟萃分析结论的稳健性，并通过亚组分析调查异质性。
在 11 项研究（2016 例患者）中，共进行了 153 例手术干预，其中经尿道前列腺切除术/激光（51.0%）、重复前列腺尿道 lifts（32.7%）和器械去除（19.6%）最为常见。每年再次手术的比率为 6.0%（95%CI 3.0-8.9）。这些结果不受任何单个研究的显著影响。每年手术干预的比率受患者随访平均时间的显著影响。在平均随访时间为 1 年或更短的研究中，手术再干预率为每年 4.3%；在平均随访时间超过 1 年至 3 年的研究中，每年为 10.7%；在一项平均随访时间超过 3 年的研究中，每年为 5.8%（p=0.04）。
前列腺尿道 lifts 术后再次手术的比率为每年 6.0%，在随访时间较长的研究中更高。
