Global Economic Dynamics and the Biosphere, Royal Swedish Academy of Sciences, Box 50005, 104 05 Stockholm, Sweden; Stockholm Resilience Centre, Stockholm University, Kräftriket 2B, 10691 Stockholm, Sweden.
Global Economic Dynamics and the Biosphere, Royal Swedish Academy of Sciences, Box 50005, 104 05 Stockholm, Sweden; Stockholm Resilience Centre, Stockholm University, Kräftriket 2B, 10691 Stockholm, Sweden; Beijer Institute of Ecological Economics, Royal Swedish Academy of Sciences, Box 50005, 104 05 Stockholm, Sweden.
Trends Ecol Evol. 2020 Jun;35(6):484-494. doi: 10.1016/j.tree.2020.01.011. Epub 2020 Mar 17.
Development of new biocides has dominated human responses to evolution of antibiotic and pesticide resistance. Increasing and uniform biocide use, the spread of resistance genes, and the lack of new classes of compounds indicate the importance of navigating toward more sustainable coevolutionary dynamics between human culture and species that evolve resistance. To inform this challenge, we introduce the concept of coevolutionary governance and propose three priorities for its implementation: (i) new norms and mental models for lowering use, (ii) diversifying practices to reduce directional selection, and (iii) investment in collective action institutions to govern connectivity. We highlight the availability of solutions that facilitate broader sustainable development, which for antibiotic resistance include improved sanitation and hygiene, strong health systems, and decreased meat consumption.
新型杀生物剂的开发一直主导着人类对抗生素和农药耐药性进化的应对措施。杀生物剂使用的不断增加和趋同、耐药基因的传播以及新型化合物类别的缺乏，都表明人类文化与具有耐药性的物种之间需要朝着更加可持续的协同进化动态发展。为了应对这一挑战，我们引入了协同进化治理的概念，并提出了实施该概念的三个优先事项：（i）降低使用量的新规范和思维模式，（ii）多样化实践以减少定向选择，以及（iii）投资于集体行动机构以进行治理。我们强调了可促进更广泛可持续发展的解决方案的可用性，这些解决方案包括改善卫生和个人卫生、加强卫生系统和减少肉类消费，以应对抗生素耐药性问题。
