Yücel Abitter, Özbuğday Yaşar
Department of Otorhinolaryngology Head and Neck Surgery, Konya Health Application and Research Center, University of Health Sciences Turkey, Konya, Turkey.
Department of Otorhinolaryngology Head and Neck Surgery, Konya Training and Research Hospital, University of Health Sciences Turkey, Konya, Turkey.
J Audiol Otol. 2020 Jul;24(3):127-132. doi: 10.7874/jao.2019.00486. Epub 2020 May 14.
In this study, we compared the outcomes of patients with idiopathic sudden sensorineural hearing loss who underwent steroid treatment with or without hyperbaric oxygen (HBO) therapy and were followed-up in our clinic.
Patients were divided into two groups according to their treatment regimen. Steroid group received intravenous 1 mg/kg methylprednisolone which was due to be completed in 2-3 weeks with decreasing doses, and five doses of 0.5 mL intratympanic dexamethasone. Steroid+HBO group received the same steroid treatment with the addition of HBO therapy. The audiologic results of both treatment groups were compared after considering the patients' risk factors.
There was no significant difference between the steroid and Steroid+HBO groups in terms of hearing gain and degree of recovery, both at all degrees of hearing loss, and in severe and profound hearing loss. Hearing gain was similar when evaluated by audiogram type and admission time in both treatment groups.
We found that the addition of HBO therapy to systemic plus intratympanic steroid treatment did not affect hearing gain at all degrees of hearing loss in this study. Furthermore, audiogram type and admission time did not affect hearing gain between the two groups.
在本研究中，我们比较了接受类固醇治疗且接受或未接受高压氧（HBO）治疗并在我们诊所进行随访的特发性突发性感音神经性听力损失患者的治疗结果。
根据治疗方案将患者分为两组。类固醇组接受静脉注射1mg/kg甲泼尼龙，预计在2 - 3周内递减剂量完成，以及五剂0.5mL鼓室内地塞米松。类固醇+HBO组接受相同的类固醇治疗并加用HBO治疗。在考虑患者风险因素后，比较两个治疗组的听力学结果。
在所有听力损失程度以及重度和极重度听力损失方面，类固醇组和类固醇+HBO组在听力增益和恢复程度方面均无显著差异。在两个治疗组中，通过听力图类型和入院时间评估时，听力增益相似。
我们发现，在本研究中，对于所有程度的听力损失，在全身加鼓室内类固醇治疗基础上加用HBO治疗并不影响听力增益。此外，听力图类型和入院时间对两组之间的听力增益没有影响。
