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Cyclin-dependent kinases as new targets for the prevention and treatment of cancer.
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RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines.
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Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences.
Genes Dev. 2019 Dec 1;33(23-24):1619-1634. doi: 10.1101/gad.331520.119. Epub 2019 Oct 8.
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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates.
Nature. 2019 Aug;572(7770):543-548. doi: 10.1038/s41586-019-1464-0. Epub 2019 Aug 7.
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Kinase inhibitors: the road ahead.
Nat Rev Drug Discov. 2018 May;17(5):353-377. doi: 10.1038/nrd.2018.21. Epub 2018 Mar 16.
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ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.
Mol Cancer Ther. 2018 Jun;17(6):1156-1166. doi: 10.1158/1535-7163.MCT-16-0847. Epub 2018 Mar 15.
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A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Hook F.
Front Pharmacol. 2018 Feb 14;9:104. doi: 10.3389/fphar.2018.00104. eCollection 2018.
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CDK9 inhibitors in acute myeloid leukemia.
J Exp Clin Cancer Res. 2018 Feb 23;37(1):36. doi: 10.1186/s13046-018-0704-8.
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Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation.
Nat Chem Biol. 2018 Feb;14(2):163-170. doi: 10.1038/nchembio.2538. Epub 2017 Dec 18.
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Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation.
EBioMedicine. 2017 Dec;26:112-125. doi: 10.1016/j.ebiom.2017.11.013. Epub 2017 Nov 21.
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c-MYC G-quadruplex binding by the RNA polymerase I inhibitor BMH-21 and analogues revealed by a combined NMR and biochemical Approach.
Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):615-629. doi: 10.1016/j.bbagen.2017.12.002. Epub 2017 Dec 8.
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The emerging roles of CDK12 in tumorigenesis.
Cell Div. 2017 Oct 27;12:7. doi: 10.1186/s13008-017-0033-x. eCollection 2017.

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