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Extracorporeal shock wave therapy to treat neurogenic heterotopic ossification in a patient with spinal cord injury: A case report.体外冲击波治疗脊髓损伤后神经源性异位骨化:病例报告。
J Spinal Cord Med. 2021 Jul;44(4):627-630. doi: 10.1080/10790268.2019.1632597. Epub 2019 Jun 26.
2
Heterotopic Ossification: A Comprehensive Review.异位骨化:全面综述
JBMR Plus. 2019 Feb 27;3(4):e10172. doi: 10.1002/jbm4.10172. eCollection 2019 Apr.
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J Bone Joint Surg Am. 2018 Feb 7;100(3):251-263. doi: 10.2106/JBJS.17.00661.
4
Heterotopic ossification: Mechanistic insights and clinical challenges.异位骨化:机制见解与临床挑战。
Bone. 2018 Apr;109:134-142. doi: 10.1016/j.bone.2017.08.025. Epub 2017 Oct 9.
5
Intramuscular Hematoma Following Radial Extracorporeal Shockwave Therapy for Chronic Neurogenic Heterotopic Ossification: A Case Report.桡侧体外冲击波治疗慢性神经源性异位骨化后发生的肌内血肿:一例报告
Ann Rehabil Med. 2017 Jun;41(3):498-504. doi: 10.5535/arm.2017.41.3.498. Epub 2017 Jun 29.
6
Neurological heterotopic ossification: Current understanding and future directions.神经异位骨化:当前的认识和未来方向。
Bone. 2018 Apr;109:35-42. doi: 10.1016/j.bone.2017.05.015. Epub 2017 May 16.
7
A preliminary investigation on the effect of extracorporeal shock wave therapy as a treatment for neurogenic heterotopic ossification following traumatic brain injury. Part II: Effects on function.体外冲击波疗法治疗创伤性脑损伤后神经源性异位骨化效果的初步研究。第二部分:对功能的影响。
Brain Inj. 2017;31(4):533-541. doi: 10.1080/02699052.2017.1283060. Epub 2017 Mar 24.
8
A preliminary investigation on the effect of extracorporeal shock wave therapy as a treatment for neurogenic heterotopic ossification following traumatic brain injury. Part I: Effects on pain.体外冲击波疗法治疗创伤性脑损伤后神经源性异位骨化效果的初步研究。第一部分:对疼痛的影响。
Brain Inj. 2017;31(4):526-532. doi: 10.1080/02699052.2017.1283059. Epub 2017 Mar 24.
9
Radial extracorporeal shock wave therapy for heterotopic ossification.桡骨体外冲击波治疗异位骨化
J Phys Ther Sci. 2016 Jan;28(2):701-4. doi: 10.1589/jpts.28.701. Epub 2016 Feb 29.
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Finite element modelling of radial shock wave therapy for chronic plantar fasciitis.慢性足底筋膜炎径向冲击波治疗的有限元建模
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长期桡骨体外冲击波治疗脊髓损伤后神经源性异位骨化:病例报告。

Long-term radial extracorporeal shock wave therapy for neurogenic heterotopic ossification after spinal cord injury: A case report.

机构信息

Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.

出版信息

J Spinal Cord Med. 2022 May;45(3):476-480. doi: 10.1080/10790268.2020.1760507. Epub 2020 May 12.

DOI:10.1080/10790268.2020.1760507
PMID:32397914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9135417/
Abstract

Heterotopic ossification is characterized by abnormal growth of bone in soft tissues. Neurogenic heterotopic ossification is also closely related to central nervous system injuries and has been reported to respond to radial extracorporeal shock wave therapy. In this case, a radial extracorporeal shock wave therapy (five times per week, lasted for almost one year) was applied to a patient with neurogenic heterotopic ossification on the left hip as a result of spinal cord injury. Throughout the treatment session, the heterotopic ossification lesion was gradually diminished, associated with the increase in joint range of motion, pain mitigation and decrease in serum alkaline phosphatase level. Long-term radial extracorporeal shock wave therapy offers a promising therapeutic alternative for neurogenic heterotopic ossification.

摘要

异位骨化的特征是软组织中异常生长的骨骼。神经源性异位骨化也与中枢神经系统损伤密切相关,已报道对放射状体外冲击波治疗有反应。在这种情况下,一名因脊髓损伤导致左侧髋关节神经源性异位骨化的患者接受了放射状体外冲击波治疗(每周 5 次,持续近一年)。在整个治疗过程中,异位骨化病变逐渐减少,关节活动度增加,疼痛减轻,血清碱性磷酸酶水平降低。长期放射状体外冲击波治疗为神经源性异位骨化提供了一种有前途的治疗选择。