• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在实施注射器服务项目后,注射阿片类药物人群的住院治疗情况。

Hospital admissions among people who inject opioids following syringe services program implementation.

机构信息

University of Miami Miller School of Medicine, Miami, USA.

Department of Medicine, University of Miami Miller School of Medicine, Miami, USA.

出版信息

Harm Reduct J. 2020 May 12;17(1):30. doi: 10.1186/s12954-020-00376-1.

DOI:10.1186/s12954-020-00376-1
PMID:32398059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7216361/
Abstract

BACKGROUND

Syringe services programs (SSPs) are an evidence-based harm reduction strategy that reduces dangerous sequelae of injection drug use among people who inject drugs (PWID) such as overdose. SSP services include safer injection education and community-based naloxone distribution programs. This study evaluates differences in overdose-associated hospital admissions following the implementation of the first legal SSP in Florida, based in Miami-Dade County.

METHODS

We performed a retrospective analysis of hospitalizations for injection drug-related sequelae at a county hospital before and after the implementation of the SSP. An algorithm utilizing ICD-10 codes for opioid use and sequelae was used to identify people who inject opioids (PWIO). Florida Department of Law Enforcement Medical Examiners Commission Report data was used to analyze concurrent overdose death trends in Florida counties.

RESULTS

Over the 25-month study period, 302 PWIO admissions were identified: 146 in the pre-index period vs. 156 in the post-index period. A total of 26 admissions with PWIO overdose were found: 20 pre-index and 6 post-index (p = 0.0034).

CONCLUSIONS

Declining overdose-associated admissions among PWIO suggests early impacts following SSP implementation. These results indicate a potential early benefit of SSP that should be further explored for its effects on future hospital admission and mortality.

摘要

背景

注射器服务项目(SSP)是一种基于证据的减少伤害策略,可减少注射吸毒者(PWID)因注射吸毒而产生的危险后果,如过量用药。SSP 服务包括更安全的注射教育和社区纳洛酮分发计划。本研究评估了佛罗里达州迈阿密-戴德县首个合法 SSP 实施后,与过量相关的住院治疗的差异。

方法

我们对一家县医院因注射药物相关后果的住院治疗情况进行了回顾性分析,在 SSP 实施前后。利用 ICD-10 代码对阿片类药物使用和后果的算法来确定注射阿片类药物的人(PWIO)。利用佛罗里达州执法部法医委员会报告的数据来分析佛罗里达州各县同期过量死亡趋势。

结果

在 25 个月的研究期间,确定了 302 例 PWIO 住院治疗:146 例在索引前期间,156 例在索引后期间。共发现 26 例 PWIO 过量的住院治疗:20 例在索引前,6 例在索引后(p = 0.0034)。

结论

PWIO 因过量而住院治疗的人数减少表明 SSP 实施后早期产生了影响。这些结果表明 SSP 具有潜在的早期效益,应进一步探讨其对未来住院和死亡率的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83e8/7216361/ca6a566f7beb/12954_2020_376_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83e8/7216361/ca6a566f7beb/12954_2020_376_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83e8/7216361/ca6a566f7beb/12954_2020_376_Fig1_HTML.jpg

相似文献

1
Hospital admissions among people who inject opioids following syringe services program implementation.在实施注射器服务项目后,注射阿片类药物人群的住院治疗情况。
Harm Reduct J. 2020 May 12;17(1):30. doi: 10.1186/s12954-020-00376-1.
2
Understanding the public health consequences of suspending a rural syringe services program: a qualitative study of the experiences of people who inject drugs.了解暂停农村注射器服务项目对公共卫生的影响:对注射毒品者的经验进行的定性研究。
Harm Reduct J. 2019 May 21;16(1):33. doi: 10.1186/s12954-019-0305-7.
3
Police officer attitudes towards syringe services programming.警察对注射器服务项目的态度。
Drug Alcohol Depend. 2019 Dec 1;205:107617. doi: 10.1016/j.drugalcdep.2019.107617. Epub 2019 Nov 3.
4
Application of machine learning algorithms for localized syringe services program policy implementation - Florida, 2017.机器学习算法在局部注射器服务项目政策实施中的应用 - 佛罗里达州,2017 年。
Ann Med. 2022 Dec;54(1):2137-2150. doi: 10.1080/07853890.2022.2105391.
5
Syringe disposal among people who inject drugs before and after the implementation of a syringe services program.在实施针具交换项目前后,注射吸毒者的注射器处理情况。
Drug Alcohol Depend. 2019 Sep 1;202:13-17. doi: 10.1016/j.drugalcdep.2019.04.025. Epub 2019 Jun 29.
6
Take-home naloxone possession among people who inject drugs in rural West Virginia.农村西弗吉尼亚州注射吸毒者携带纳洛酮回家的情况。
Drug Alcohol Depend. 2019 Nov 1;204:107581. doi: 10.1016/j.drugalcdep.2019.107581. Epub 2019 Sep 21.
7
High uptake of naloxone-based overdose prevention training among previously incarcerated syringe-exchange program participants.在曾被监禁的注射器交换项目参与者中,基于纳洛酮的过量用药预防培训参与率很高。
Drug Alcohol Depend. 2015 Sep 1;154:283-6. doi: 10.1016/j.drugalcdep.2015.06.023. Epub 2015 Jun 24.
8
Unmet needs and harm reduction preferences of syringe services program participants: differences by co-use of illicit opioids and methamphetamine.未满足的需求和减少危害偏好的注射毒品者:同时使用非法阿片类药物和冰毒的差异。
Harm Reduct J. 2024 Jun 19;21(1):119. doi: 10.1186/s12954-024-01038-2.
9
Fatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland.致命性药物过量预防和纳洛酮使用经验:马里兰州巴尔的摩市一个基于社区的注射吸毒者队列的横断面研究。
PLoS One. 2020 Mar 11;15(3):e0230127. doi: 10.1371/journal.pone.0230127. eCollection 2020.
10
Baseline prevalence and correlates of HIV and HCV infection among people who inject drugs accessing a syringe services program; Miami, FL.在接受注射毒品者服务计划的吸毒者中,艾滋病毒和丙型肝炎病毒感染的基线流行率和相关因素;佛罗里达州迈阿密。
Harm Reduct J. 2020 Jun 10;17(1):40. doi: 10.1186/s12954-020-00385-0.

引用本文的文献

1
Exploration of novel harm reduction approaches to increase client engagement (ENHANCE): protocol for a prospective cohort study.探索增加服务对象参与度的新型减少伤害方法(ENHANCE):一项前瞻性队列研究的方案
Harm Reduct J. 2025 May 19;22(Suppl 1):81. doi: 10.1186/s12954-025-01212-0.
2
A systematic review of macro-, meso, and micro-level harm reduction interventions addressing the U.S. opioid overdose epidemic.一项针对美国阿片类药物过量流行问题的宏观、中观和微观层面减少伤害干预措施的系统综述。
Drugs (Abingdon Engl). 2025;32(1):1-14. doi: 10.1080/09687637.2024.2306826. Epub 2024 Jan 23.
3
Community-Based Services for Hospitalized Patients With Serious Injection-Related Infections in Alabama: A Brief Report.

本文引用的文献

1
Prevalence and correlates of carrying naloxone among a community-based sample of opioid-using people who inject drugs.社区中使用阿片类药物注射的人群中携带纳洛酮的流行率及其相关因素。
Int J Drug Policy. 2019 Nov;73:32-35. doi: 10.1016/j.drugpo.2019.07.010. Epub 2019 Jul 20.
2
Drug and Opioid-Involved Overdose Deaths - United States, 2013-2017.药物和阿片类药物滥用相关的过量死亡-美国,2013-2017 年。
MMWR Morb Mortal Wkly Rep. 2018 Jan 4;67(5152):1419-1427. doi: 10.15585/mmwr.mm675152e1.
3
Naloxone Effectiveness: A Systematic Review.
阿拉巴马州针对患有严重注射相关感染的住院患者的社区服务:简要报告
Open Forum Infect Dis. 2024 Apr 24;11(5):ofae231. doi: 10.1093/ofid/ofae231. eCollection 2024 May.
4
Applications of research evidence during processes to acquire approvals for syringe services program implementation in rural counties in Kentucky.肯塔基州农村县实施注射器服务项目审批过程中研究证据的应用。
Ann Med. 2022 Dec;54(1):404-412. doi: 10.1080/07853890.2022.2028001.
5
Harm reduction for the treatment of patients with severe injection-related infections: description of the Jackson SIRI Team.减少危害以治疗严重注射相关感染的患者:杰克逊 SIRI 团队的描述。
Ann Med. 2021 Dec;53(1):1960-1968. doi: 10.1080/07853890.2021.1993326.
纳洛酮的有效性:一项系统评价。
J Addict Nurs. 2018 Jul/Sep;29(3):167-171. doi: 10.1097/JAN.0000000000000230.
4
Toots, tastes and tester shots: user accounts of drug sampling methods for gauging heroin potency.嘬、尝、试吸:用户描述的用于评估海洛因效力的毒品抽样方法。
Harm Reduct J. 2018 May 16;15(1):26. doi: 10.1186/s12954-018-0232-z.
5
Effects of naloxone distribution to likely bystanders: Results of an agent-based model.纳洛酮向可能的旁观者分发的效果:基于主体的模型的结果。
Int J Drug Policy. 2018 May;55:61-69. doi: 10.1016/j.drugpo.2018.02.008. Epub 2018 Mar 20.
6
From Peers to Lay Bystanders: Findings from a Decade of Naloxone Distribution in Pittsburgh, PA.从同行到普通旁观者:宾夕法尼亚州匹兹堡十年来纳洛酮分发的研究结果。
J Psychoactive Drugs. 2018 Jul-Aug;50(3):240-246. doi: 10.1080/02791072.2018.1430409. Epub 2018 Feb 9.
7
Assessing causality in drug policy analyses: How useful are the Bradford Hill criteria in analysing take-home naloxone programs?评估药物政策分析中的因果关系:布拉德福·希尔标准在分析纳洛酮家庭用药方案中有多大用处?
Drug Alcohol Rev. 2018 May;37(4):499-501. doi: 10.1111/dar.12523. Epub 2017 Apr 18.
8
Effectiveness of bystander naloxone administration and overdose education programs: a meta-analysis.旁观者给予纳洛酮及过量用药教育项目的有效性:一项荟萃分析。
Inj Epidemiol. 2015 Dec;2(1):10. doi: 10.1186/s40621-015-0041-8. Epub 2015 May 22.
9
Are take-home naloxone programmes effective? Systematic review utilizing application of the Bradford Hill criteria.带回家的纳洛酮项目有效吗?运用布拉德福德·希尔标准进行的系统评价。
Addiction. 2016 Jul;111(7):1177-87. doi: 10.1111/add.13326. Epub 2016 Mar 30.
10
Effect of Florida's Prescription Drug Monitoring Program and Pill Mill Laws on Opioid Prescribing and Use.佛罗里达州的处方药监测计划和“药丸工厂”法对阿片类药物处方和使用的影响。
JAMA Intern Med. 2015 Oct;175(10):1642-9. doi: 10.1001/jamainternmed.2015.3931.