The Division of Upper GI and General Surgery at the University of Southern California, Los Angeles, California, USA.
Curr Opin Gastroenterol. 2020 Jul;36(4):323-328. doi: 10.1097/MOG.0000000000000643.
The purpose of this magnetic sphincter augmentation (MSA) year in review article is to provide a clear understanding for the current state of MSA literature in 2019, and contrast MSA outcomes with traditional fundoplication.
Continued work was performed in 2019 to expand patient populations eligible for MSA including those with hiatal hernia, post-bariatric patients, patients necessitating a thoracic approach, and patients with esophageal intestinal metaplasia. Additionally, a large systematic review reinforced earlier findings comparing laparoscopic fundoplication to MSA. This study demonstrated equivalency over many different operative outcomes, with MSA patients having less bloating while also retaining the ability to belch and vomit. Furthermore, independent research teams found a modest cost savings for MSA over laparoscopic fundoplication with budget analysis.
MSA is a safe and efficacious procedure originally approved for patients with medically refractory, uncomplicated gastroesophageal reflux disease. The accumulating body of evidence suggests patients with intestinal metaplasia or hiatal hernias can safely and effectively undergo MSA, whereas further research will be required before MSA is widely used for post-bariatric patients or for patients requiring a transthoracic surgical approach. MSA is equivalent or superior to laparoscopic fundoplication in all surgical outcomes measured thus far.
本文旨在介绍 2019 年磁括约肌增强术(MSA)的研究进展,对比 MSA 与传统胃底折叠术的治疗效果。
2019 年,MSA 的适用人群进一步扩大,包括合并食管裂孔疝、减重术后、需要开胸手术及合并食管肠化生的患者。此外,一项大型系统综述再次证实了腹腔镜胃底折叠术与 MSA 之间的疗效相当,MSA 患者术后腹胀更少,同时仍能打嗝和呕吐。此外,通过预算分析,独立研究团队发现 MSA 相较于腹腔镜胃底折叠术具有一定的成本节约优势。
MSA 是一种安全有效的术式,最初被批准用于治疗药物难治性、单纯性胃食管反流病患者。目前的证据表明,合并肠化生或食管裂孔疝的患者可以安全有效地接受 MSA 治疗,但在 MSA 广泛应用于减重术后患者或需要经胸手术入路的患者之前,还需要进一步的研究。在迄今为止测量的所有手术结果中,MSA 与腹腔镜胃底折叠术相当或更优。