Division of Gastroenterology, Duke University School of Medicine and the Durham VA Medical Center, Durham, NC, USA.
Division of Gastroenterology, Washington University School of Medicine, Saint Louis, MO, USA.
Dis Esophagus. 2023 Jun 15;36(Supplement_1). doi: 10.1093/dote/doad005.
Magnetic sphincter augmentation (MSA) is a surgical intervention for well-characterized gastroesophageal reflux disease (GERD), where the esophagogastric junction barrier is augmented using a bracelet of magnetized titanium beads. MSA could be an attractive option for patients with documented GERD who wish to avoid long-term pharmacologic therapy or whose symptoms are not adequately managed with lifestyle modifications and pharmacologic therapy. The 'ideal' MSA patient is one with prominent regurgitation, without dysphagia or esophageal motor dysfunction, with objective evidence of GERD on upper endoscopy and/or ambulatory reflux monitoring. Appropriate candidates with significant hiatus hernia may pursue MSA with concomitant hiatus hernia repair. The increasing adoption of MSA in the GERD treatment pathway reflects research that shows benefits in long-term outcomes and healthcare costs compared with other established therapies in appropriate clinical settings.
磁括约肌增强术(MSA)是一种针对明确诊断的胃食管反流病(GERD)的手术干预方法,通过使用磁化钛珠环来增强食管胃交界处的屏障。对于那些希望避免长期药物治疗或生活方式改变和药物治疗不能充分控制症状的有记录的 GERD 患者,MSA 可能是一个有吸引力的选择。“理想的”MSA 患者是那些有明显反流而没有吞咽困难或食管运动功能障碍的患者,在上消化道内镜检查和/或动态反流监测中有 GERD 的客观证据。有明显食管裂孔疝的合适患者可以进行 MSA 治疗,同时进行食管裂孔疝修补术。MSA 在 GERD 治疗途径中的应用越来越多,这反映了研究结果,即在适当的临床环境下,与其他已确立的治疗方法相比,MSA 在长期结果和医疗保健成本方面具有优势。