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磁括约肌增强术在胃食管反流病治疗途径中的作用:胃肠病学视角。

The role of magnetic sphincter augmentation in the gastroesophageal reflux disease treatment pathway: the gastroenterology perspective.

机构信息

Division of Gastroenterology, Duke University School of Medicine and the Durham VA Medical Center, Durham, NC, USA.

Division of Gastroenterology, Washington University School of Medicine, Saint Louis, MO, USA.

出版信息

Dis Esophagus. 2023 Jun 15;36(Supplement_1). doi: 10.1093/dote/doad005.

DOI:10.1093/dote/doad005
PMID:36776100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10267695/
Abstract

Magnetic sphincter augmentation (MSA) is a surgical intervention for well-characterized gastroesophageal reflux disease (GERD), where the esophagogastric junction barrier is augmented using a bracelet of magnetized titanium beads. MSA could be an attractive option for patients with documented GERD who wish to avoid long-term pharmacologic therapy or whose symptoms are not adequately managed with lifestyle modifications and pharmacologic therapy. The 'ideal' MSA patient is one with prominent regurgitation, without dysphagia or esophageal motor dysfunction, with objective evidence of GERD on upper endoscopy and/or ambulatory reflux monitoring. Appropriate candidates with significant hiatus hernia may pursue MSA with concomitant hiatus hernia repair. The increasing adoption of MSA in the GERD treatment pathway reflects research that shows benefits in long-term outcomes and healthcare costs compared with other established therapies in appropriate clinical settings.

摘要

磁括约肌增强术(MSA)是一种针对明确诊断的胃食管反流病(GERD)的手术干预方法,通过使用磁化钛珠环来增强食管胃交界处的屏障。对于那些希望避免长期药物治疗或生活方式改变和药物治疗不能充分控制症状的有记录的 GERD 患者,MSA 可能是一个有吸引力的选择。“理想的”MSA 患者是那些有明显反流而没有吞咽困难或食管运动功能障碍的患者,在上消化道内镜检查和/或动态反流监测中有 GERD 的客观证据。有明显食管裂孔疝的合适患者可以进行 MSA 治疗,同时进行食管裂孔疝修补术。MSA 在 GERD 治疗途径中的应用越来越多,这反映了研究结果,即在适当的临床环境下,与其他已确立的治疗方法相比,MSA 在长期结果和医疗保健成本方面具有优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df71/10267695/393eeba46ded/doad005f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df71/10267695/393eeba46ded/doad005f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df71/10267695/393eeba46ded/doad005f1.jpg

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Surg Endosc. 2022 Nov;36(11):8255-8260. doi: 10.1007/s00464-022-09261-3. Epub 2022 Apr 26.
2
The Impact of Magnetic Sphincter Augmentation (MSA) on Esophagogastric Junction (EGJ) and Esophageal Body Physiology and Manometric Characteristics.磁括约肌增强术(MSA)对食管胃结合部(EGJ)和食管体生理学及测压特征的影响。
Ann Surg. 2023 Mar 1;277(3):e545-e551. doi: 10.1097/SLA.0000000000005239. Epub 2021 Oct 8.
3
AGA Clinical Practice Update on the Personalized Approach to the Evaluation and Management of GERD: Expert Review.
AGA 临床实践更新:胃食管反流病评估和管理的个体化方法:专家综述。
Clin Gastroenterol Hepatol. 2022 May;20(5):984-994.e1. doi: 10.1016/j.cgh.2022.01.025. Epub 2022 Feb 2.
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ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.美国胃肠病学会胃食管反流病诊断和管理临床指南
Am J Gastroenterol. 2022 Jan 1;117(1):27-56. doi: 10.14309/ajg.0000000000001538.
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Gastroenterol Hepatol (N Y). 2021 Jul;17(7):305-315.
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