Loiudice Pasquale, Montesel Andrea, Sartini Francesco, Morganti Riccardo, Posarelli Chiara, Nardi Marco, Figus Michele, Casini Giamberto
Ophthalmology Unit, Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy.
Department of Clinical and Experimental Medicine, Section of Statistics, University of Pisa, Pisa, Italy.
Eye (Lond). 2021 Mar;35(3):786-790. doi: 10.1038/s41433-020-0950-9. Epub 2020 May 12.
BACKGROUND/OBJECTIVES: To compare the efficacy of intraoperative localized and 360° laser retinopexy in cases of rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy and air tamponade.
SUBJECTS/METHODS: In this interventional, prospective, randomized, comparative study, 93 consecutive cases of RRD were enroled. After randomization 48 eyes received circumferential, while 45 underwent localized intraoperative laser retinopexy. Number and position of the retinal breaks, presence of proliferative vitreoretinopathy and/or lattice degeneration were recorded. Anatomical and visual outcome of the two groups were compared at 6 months postoperatively.
Baseline characteristics did not significantly differ between groups. The single-operation reattachment rate was 86.66% in localized group and 89.58% in 360° group. The difference was not significant. (P = 0.46, χ test). At 6 months postoperatively, visual acuity (logMAR) was 0.06 ± 0.05 in localized group and 0.05 ± 0.03 in 360° group. The difference was not statistically significant (P = 0.673, t-test).
Localized laser resulted to be as effective as 360° laser application; this may lead some advantages in term of lower invasiveness, reduction risk of complications and time saving.
背景/目的:比较在接受玻璃体切割术和空气填塞治疗的孔源性视网膜脱离(RRD)病例中,术中局部激光视网膜光凝与360°激光视网膜光凝的疗效。
受试者/方法:在这项干预性、前瞻性、随机对照比较研究中,连续纳入93例RRD患者。随机分组后,48只眼接受环形激光视网膜光凝,45只眼接受术中局部激光视网膜光凝。记录视网膜裂孔的数量和位置、增殖性玻璃体视网膜病变和/或格子样变性的存在情况。比较两组术后6个月的解剖和视觉结果。
两组的基线特征无显著差异。局部激光光凝组的单次手术复位率为86.66%,360°激光光凝组为89.58%。差异无统计学意义(P = 0.46,χ检验)。术后6个月,局部激光光凝组的视力(logMAR)为0.06±0.05,360°激光光凝组为0.05±0.03。差异无统计学意义(P = 0.673,t检验)。
局部激光光凝与360°激光光凝效果相同;这在降低侵袭性、减少并发症风险和节省时间方面可能具有一些优势。