Natural Products Research Unit, Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand.
School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, New South Wales, Australia.
Nat Prod Res. 2021 Nov;35(21):3908-3917. doi: 10.1080/14786419.2020.1749611. Epub 2020 May 13.
A new secoiridoid glycoside, 3'----coumaroylsweroside (), together with twenty-nine compounds (-), were isolated from the roots and flowers of Roxb. (Gentianaceae). Their structures were identified by analysis of mass spectrometric and NMR spectroscopic data. Compounds , , , and - showed weak to moderate cytotoxicity against cholangiocarcinoma cancer cells lines (KKU-213, KKU-055 and KKU-214). We report the first phytochemical investigation of the roots and flowers of , as only the essential oil of the latter has been investigated.
从秦艽（Gentianaceae）的根和花中分离得到了一种新的裂环环烯醚萜苷，3'----咖啡酰sweroside（），以及另外 29 种化合物（-）。通过分析质谱和 NMR 光谱数据确定了它们的结构。化合物、、、和-对胆管癌细胞系（KKU-213、KKU-055 和 KKU-214）表现出弱到中等的细胞毒性。我们报告了对的根和花的首次植物化学研究，因为只对后者的精油进行了研究。
