Department of Environmental Engineering, Faculty of Process and Environmental Engineering, Lodz University of Technology, Lodz, Poland.
Mini Rev Med Chem. 2020;20(16):1619-1632. doi: 10.2174/1389557520666200513120407.
The currently observed development of medical science results from the constant search for innovative solutions to improve the health and quality of life of patients. Particular attention is focused on the design of a new generation of materials with a high degree of biocompatibility and tolerance towards the immune system. In addition, apart from biotolerance, it is important to ensure appropriate mechanical and technological properties of materials intended for intra-body applications. Knowledge of the above parameters becomes the basis for considerations related to the possibilities of choosing the appropriate polymer materials. The researchers' interest, as evidenced by the number of available publications, is attracted by nanobiocomposites based on chitosan and carbon nanotubes, which, due to their properties, enable integration with the tissues of the human body. Nanosystems can be used in many areas of medicine. They constitute an excellent base for use as dressing materials, as they exhibit antimicrobial properties. In addition, they can be carriers of drugs and biological macromolecules and can be used in gene therapy, tissue engineering, and construction of biosensors. For this reason, potential application areas of chitosan-carbon nanotube nanocomposites in medical sciences are presented in this publication, considering the characteristics of the system components.
目前医学科学的发展源于不断寻求创新解决方案,以提高患者的健康和生活质量。特别关注的是设计具有高度生物相容性和对免疫系统耐受性的新一代材料。此外,除了生物耐受性外,确保用于体内应用的材料具有适当的机械和技术性能也很重要。这些参数的知识是与选择合适的聚合物材料的可能性相关的考虑的基础。研究人员的兴趣,从现有的出版物数量就可以看出,被基于壳聚糖和碳纳米管的纳米生物复合材料所吸引,由于其特性,这些复合材料能够与人体组织集成。纳米系统可用于医学的许多领域。它们是用作敷料材料的极好基础,因为它们具有抗菌性能。此外,它们可以作为药物和生物大分子的载体,并可用于基因治疗、组织工程和生物传感器的构建。出于这个原因,考虑到系统组件的特性,本出版物介绍了壳聚糖-碳纳米管纳米复合材料在医学科学中的潜在应用领域。