From the SDA Bocconi School of Management, Bocconi University, Milan, Italy.
Leo Pharma, Ballerup, Denmark.
Dermatitis. 2020 May/Jun;31(3):178-184. doi: 10.1097/DER.0000000000000598.
: The aim of this study was to conduct 3 literature reviews to examine the impact of atopic dermatitis (AD) and chronic hand eczema (CHE) on health-related quality of life (HRQoL) compared with other chronic conditions by comparing reported utility scores of 4 commonly used generic HRQoL instruments. A systematic search was performed using PubMed, ScienceDirect, MEDLINE, EMBASE, Health Technology Assessment database, and ScHARRHUD. Inclusion criteria included, but were not limited to, patients of any age, studies from any location, publications reporting utility data based on EuroQoL 5 dimensions, the EuroQoL 5-dimension Visual Analog Scale, the Short-Form Health Survey, and the Short-Form 6 Dimensions in the English language. Inclusion criteria were met by 16 articles for AD, 25 articles for chronic conditions, and 9 articles for CHE. The findings of this review highlight that the disutility and loss in HRQoL of patients with AD and CHE are similar to or higher than other chronic conditions, such as cancer or hepatitis.
本研究旨在进行 3 项文献综述，通过比较 4 种常用通用健康相关生活质量（HRQoL）工具报告的效用评分，来评估特应性皮炎（AD）和慢性手部湿疹（CHE）对 HRQoL 的影响与其他慢性疾病相比。使用 PubMed、ScienceDirect、MEDLINE、EMBASE、卫生技术评估数据库和 ScHARRHUD 进行了系统检索。纳入标准包括但不限于任何年龄的患者、来自任何地点的研究、报告基于欧洲五维健康量表（EQ-5D）、欧洲五维健康量表视觉模拟量表（EQ-VAS）、健康调查简表（SF-36）和简短健康调查问卷-6 维度（SF-6D）的效用数据的出版物。有 16 篇 AD 相关文章、25 篇慢性疾病相关文章和 9 篇 CHE 相关文章符合纳入标准。本综述的研究结果表明，AD 和 CHE 患者的 HRQoL 损失和降低与其他慢性疾病（如癌症或肝炎）相似或更高。
