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手部皮炎:巴西一家三级转诊医院的6年经验

Hand dermatitis: a 6-year experience in a tertiary referral Brazilian hospital.

作者信息

Endlich Larissa Relva da Fonte Gonçalves, Samorano Luciana Paula, Nunes Ricardo Spina, Reis Vitor Manoel Silva Dos

机构信息

Department of Dermatology, Hospital das Clínicas, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

Department of Dermatology, Hospital das Clínicas, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

An Bras Dermatol. 2025 May-Jun;100(3):439-446. doi: 10.1016/j.abd.2024.08.010. Epub 2025 Mar 29.

Abstract

BACKGROUND

Hand dermatitis (HD) is a prevalent inflammatory skin disease with a significant socioeconomic impact.

OBJECTIVES

To characterize the population of HD patients followed up at the Department of Dermatology of a tertiary hospital.

METHODS

A cross-sectional, retrospective and descriptive study was carried out through the analysis of medical records of HD patients assisted at the Allergy Clinic of the Department of Dermatology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, between March 1, 2016 and August 31, 2022.

RESULTS

Of the 175 patients, 73.3% were women, and the mean age at the onset of the condition was 41.7 years. There was a statistically significant association between occupation categories and the presence of occupational dermatitis. Cases were classified as irritant contact dermatitis (49.7%), allergic contact dermatitis (57.1%) and endogenous vesicular HD (3.4%). It was observed a statistically significant higher frequency of patch tests positivity for methylchloroisothiazolinone and methylisothiazolinone (MCI/MI) and nickel sulfate in women and for potassium bichromate and carba mix in men. DLQI was assessed in 77 patients, and the average score was 7.8 points.

STUDY LIMITATIONS

As limitations, the authors point out data collection from medical records, which lacked some information. Furthermore, as this was a cross-sectional study, it was not possible to assess cause-and-effect relationships between the variables.

CONCLUSIONS

The present data reinforces the importance of patch tests in HD investigation and highlights the high sensitivity rates to MCI/MI and nickel sulfate in Brazilian women and to potassium bichromate and carba mix in Brazilian men patients.

摘要

背景

手部皮炎(HD)是一种常见的炎症性皮肤病,具有重大的社会经济影响。

目的

对一家三级医院皮肤科随访的HD患者群体进行特征描述。

方法

通过分析2016年3月1日至2022年8月31日期间在圣保罗大学医学院临床医院皮肤科过敏诊所就诊的HD患者的病历,开展了一项横断面、回顾性和描述性研究.

结果

在175例患者中,73.3%为女性,发病时的平均年龄为41.7岁。职业类别与职业性皮炎的存在之间存在统计学上的显著关联。病例分为刺激性接触性皮炎(49.7%)、过敏性接触性皮炎(57.1%)和内源性水疱性HD(3.4%)。观察到女性对甲基氯异噻唑啉酮和甲基异噻唑啉酮(MCI/MI)以及硫酸镍的斑贴试验阳性频率在统计学上显著较高,男性对重铬酸钾和卡巴混合物的斑贴试验阳性频率在统计学上显著较高。对77例患者进行了DLQI评估;平均得分为7.8分。

研究局限性

作者指出,作为局限性,数据是从病历中收集而来,缺乏一些信息。此外,由于这是一项横断面研究,无法评估变量之间的因果关系。

结论

目前的数据强化了斑贴试验在HD调查中的重要性,并突出了巴西女性对MCI/MI和硫酸镍以及巴西男性患者对重铬酸钾和卡巴混合物的高敏感率。

相似文献

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Hand dermatitis: a 6-year experience in a tertiary referral Brazilian hospital.手部皮炎:巴西一家三级转诊医院的6年经验
An Bras Dermatol. 2025 May-Jun;100(3):439-446. doi: 10.1016/j.abd.2024.08.010. Epub 2025 Mar 29.
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Interventions for preventing occupational irritant hand dermatitis.预防职业性刺激性手部皮炎的干预措施。
Cochrane Database Syst Rev. 2018 Apr 30;4(4):CD004414. doi: 10.1002/14651858.CD004414.pub3.
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Interventions for preventing occupational irritant hand dermatitis.预防职业性刺激性手部皮炎的干预措施。
Cochrane Database Syst Rev. 2010 Jun 16(6):CD004414. doi: 10.1002/14651858.CD004414.pub2.

本文引用的文献

8
Patch Testing to Diphenylguanidine by the North American Contact Dermatitis Group (2013-2016).
Dermatitis. 2020 Nov-Dec;31(6):350-358. doi: 10.1097/DER.0000000000000629.

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