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血液透析患者中心静脉闭塞再通的结局及成功预测因素:一项回顾性研究

Outcome of Central Vein Occlusion Recanalization in Hemodialysis Patients and Predictors for Success: A Retrospective Study.

作者信息

Hongsakul Keerati, Leelarujijaroen Pattarasuda, Boonsrirat Ussanee

机构信息

Prince of Songkla University, TH.

出版信息

J Belg Soc Radiol. 2020 May 6;104(1):20. doi: 10.5334/jbsr.1991.

Abstract

BACKGROUND

Catheter-directed treatment is the standard approach for the management of chronic central venous occlusion.

PURPOSE

The objective of this study is to report the outcome of conventional recanalization of chronic central vein occlusion in hemodialysis patients and to determine the predictors for success.

MATERIAL AND METHODS

All hemodialysis patients who underwent endovascular recanalization of central vein occlusion from January 2012 to December 2016 were retrospectively evaluated. The procedure was percutaneous transluminal angioplasty. Stenting was performed in case of a significant recoil stenosis. Kaplan-Meier analysis was used to evaluate central vein patency. Univariate analysis and multivariate logistic regression were used to calculate the predictive factors.

RESULTS

Ninety-seven patients (mean age, 61.2 years; range, 25‒89 years old) with 97 central vein occlusions were enrolled. Technical success was achieved in 49 patients (50.5%). The primary patency rates of central veins at 6 and 12 months were achieved in 17 patients (34.4%) and 8 patients (15.8%), respectively. The assisted primary patency rates at 6 and 12 months were achieved in 38 patients (77.3%) and 30 patients (61%), respectively. Patient age ≥60 years and a tapered-type of lesion were significant predictive factors for successful recanalization.

CONCLUSION

Endovascular treatment of the central vein occlusion using a conventional technique is moderately effective and safe. Angioplasty alone and stenting were not significantly different in terms of patency rate. The age of the patients and type of occlusion were significant predictors for successful recanalization.

摘要

背景

导管定向治疗是慢性中心静脉闭塞管理的标准方法。

目的

本研究的目的是报告血液透析患者慢性中心静脉闭塞传统再通的结果,并确定成功的预测因素。

材料与方法

回顾性评估2012年1月至2016年12月期间接受中心静脉闭塞血管腔内再通的所有血液透析患者。该手术为经皮腔内血管成形术。出现明显回缩性狭窄时进行支架置入。采用Kaplan-Meier分析评估中心静脉通畅情况。单因素分析和多因素逻辑回归用于计算预测因素。

结果

纳入97例中心静脉闭塞的患者(平均年龄61.2岁;范围25 - 89岁)。49例患者(50.5%)获得技术成功。中心静脉6个月和12个月的初级通畅率分别为17例患者(34.4%)和8例患者(15.8%)。6个月和12个月的辅助初级通畅率分别为38例患者(77.3%)和30例患者(61%)。患者年龄≥60岁和病变呈锥形是成功再通的重要预测因素。

结论

采用传统技术对中心静脉闭塞进行血管腔内治疗具有中等疗效且安全。单纯血管成形术和支架置入术在通畅率方面无显著差异。患者年龄和闭塞类型是成功再通的重要预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ab/7207257/4673e5caf1b2/jbsr-104-1-1991-g1.jpg

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