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On the origin and continuing evolution of SARS-CoV-2.关于严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的起源及持续进化
Natl Sci Rev. 2020 Jun;7(6):1012-1023. doi: 10.1093/nsr/nwaa036. Epub 2020 Mar 3.
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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.羟氯喹和阿奇霉素治疗 COVID-19:一项开放标签非随机临床试验的结果。
Int J Antimicrob Agents. 2020 Jul;56(1):105949. doi: 10.1016/j.ijantimicag.2020.105949. Epub 2020 Mar 20.
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A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.洛匹那韦-利托那韦治疗成人重症 COVID-19 患者的临床试验。
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Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow?妊娠期新型冠状病毒病(COVID-19):应遵循哪些临床建议?
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A Case Series of Children With 2019 Novel Coronavirus Infection: Clinical and Epidemiological Features.儿童 2019 年新型冠状病毒感染病例系列:临床和流行病学特征。
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Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases.中国 2019 年冠状病毒病(COVID-19)的胸部 CT 与 RT-PCR 检测的相关性:1014 例报告。
Radiology. 2020 Aug;296(2):E32-E40. doi: 10.1148/radiol.2020200642. Epub 2020 Feb 26.
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Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China.新型冠状病毒肺炎(SARS-CoV-2)感染的癌症患者:一项中国全国性分析。
Lancet Oncol. 2020 Mar;21(3):335-337. doi: 10.1016/S1470-2045(20)30096-6. Epub 2020 Feb 14.
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Respiratory Virus Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient.造血系统恶性肿瘤患者与干细胞移植受者的呼吸道病毒感染
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Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?癌症患者的淋巴细胞减少症及其对免疫治疗反应的影响:与细胞因子联合的机会?
J Immunother Cancer. 2019 Mar 28;7(1):85. doi: 10.1186/s40425-019-0549-5.

新冠病毒疾病与癌症患者。

COVID-19 and Cancer Patients.

作者信息

Patel Rajvi, Park Jennifer, Shah Ankit, Saif Muhammad Wasif

机构信息

Department of Medical Oncology, Northwell Health Cancer Institute, Donald and Barbara Zucker School of Medicine at Hofstra and Feinstein Institute for Medical Research, USA.

出版信息

Cancer Med J. 2020;3(1):40-48. Epub 2020 Apr 3.

PMID:32405629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7219960/
Abstract

COVID-19 has now been declared a global pandemic with evolving incidence rates and fatalities. It is important to identify vulnerable populations who will be impacted most by this pandemic leading to higher mortality rates compared to the general healthy population. Although older patients and patients with co-morbidities fall into this vulnerable group, patients with hematologic and oncologic malignancies on active cytotoxic treatments are at even greater risk as they are both myelosuppressed and immunosuppressed. In addition to following the universal guidelines recommended by the Centers for Disease Control (CDC), it is important to also institute guidelines for cancer centers to help protect this vulnerable population. We review the current data, risks, and recommendations for COVID-19 in cancer patients.

摘要

新型冠状病毒肺炎(COVID-19)现已被宣布为全球大流行疾病,其发病率和死亡率不断变化。识别那些与一般健康人群相比,将受到此次大流行影响最大、死亡率更高的脆弱人群至关重要。虽然老年患者和患有合并症的患者属于这一脆弱群体,但正在接受积极细胞毒性治疗的血液系统和肿瘤恶性肿瘤患者面临的风险更大,因为他们既有骨髓抑制又有免疫抑制。除遵循疾病控制中心(CDC)推荐的通用指南外,为癌症中心制定指导方针以帮助保护这一脆弱人群也很重要。我们回顾了癌症患者中COVID-19的当前数据、风险和建议。