儿童 2019 年新型冠状病毒感染病例系列：临床和流行病学特征。
A Case Series of Children With 2019 Novel Coronavirus Infection: Clinical and Epidemiological Features.
机构信息
Department of Infectious Diseases, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Divison of Virology, Department of Clinical Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
出版信息
Clin Infect Dis. 2020 Sep 12;71(6):1547-1551. doi: 10.1093/cid/ciaa198.
Abstract
We first described the 2019 novel coronavirus infection in 10 children occurring in areas other than Wuhan. The coronavirus diseases in children are usually mild and epidemiological exposure is a key clue to recognize pediatric case. Prolonged virus shedding is observed in respiratory tract and feces at the convalescent stage.
摘要
我们首次描述了发生在武汉以外地区的 10 例儿童 2019 新型冠状病毒感染。儿童的冠状病毒疾病通常较轻，流行病学接触是识别儿科病例的关键线索。在恢复期，呼吸道和粪便中可观察到病毒持续排出。
相似文献
1
A Case Series of Children With 2019 Novel Coronavirus Infection: Clinical and Epidemiological Features.儿童 2019 年新型冠状病毒感染病例系列：临床和流行病学特征。
Clin Infect Dis. 2020 Sep 12;71(6):1547-1551. doi: 10.1093/cid/ciaa198.
2
A Case Series of Children With Coronavirus Disease 2019: What Have We Learned?2019年冠状病毒病患儿病例系列：我们学到了什么？
Clin Infect Dis. 2020 Sep 12;71(6):1552-1553. doi: 10.1093/cid/ciaa469.
3
Duration of Respiratory and Gastrointestinal Viral Shedding in Children With SARS-CoV-2: A Systematic Review and Synthesis of Data.儿童 SARS-CoV-2 呼吸道和胃肠道病毒脱落持续时间：系统评价和数据综合。
Pediatr Infect Dis J. 2020 Sep;39(9):e249-e256. doi: 10.1097/INF.0000000000002814.
4
Gastrointestinal involvement of COVID-19 and potential faecal transmission of SARS-CoV-2.COVID-19 对胃肠道的影响和 SARS-CoV-2 的潜在粪便传播。
J Zhejiang Univ Sci B. 2020;21(9):749-751. doi: 10.1631/jzus.B2000253.
5
Symptomatic Infection is Associated with Prolonged Duration of Viral Shedding in Mild Coronavirus Disease 2019: A Retrospective Study of 110 Children in Wuhan.症状性感染与轻度 2019 年冠状病毒病（COVID-19）患者病毒脱落时间延长有关：武汉 110 例儿童的回顾性研究。
Pediatr Infect Dis J. 2020 Jul;39(7):e95-e99. doi: 10.1097/INF.0000000000002729.
6
Prolonged presence of SARS-CoV-2 viral RNA in faecal samples.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒RNA在粪便样本中的长期存在。
Lancet Gastroenterol Hepatol. 2020 May;5(5):434-435. doi: 10.1016/S2468-1253(20)30083-2. Epub 2020 Mar 20.
7
Dynamic Viral Severe Acute Respiratory Syndrome Coronavirus 2 RNA Shedding in Children: Preliminary Data and Clinical Consideration from a Italian Regional Center.儿童中病毒 RNA 动态持续性排出的严重急性呼吸综合征冠状病毒 2：来自意大利一个地区中心的初步数据和临床观察。
J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):366-369. doi: 10.1093/jpids/piaa065.
8
The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients.SARS-CoV-2 RNA 存在于 COVID-19 患者的粪便中。
J Med Virol. 2020 Jul;92(7):833-840. doi: 10.1002/jmv.25825. Epub 2020 Apr 25.
9
Duration of SARS-CoV-2 viral shedding during COVID-19 infection.新型冠状病毒肺炎（COVID-19）感染期间严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒脱落的持续时间。
Infect Dis (Lond). 2020 Jul;52(7):511-512. doi: 10.1080/23744235.2020.1748705. Epub 2020 Apr 10.
10
Prolonged shedding of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) RNA among patients with coronavirus disease 2019 (COVID-19).2019冠状病毒病（COVID-19）患者中严重急性呼吸综合征冠状病毒2（SARS-CoV-2）RNA的长期脱落
Infect Control Hosp Epidemiol. 2020 Oct;41(10):1235-1236. doi: 10.1017/ice.2020.307. Epub 2020 Jun 24.
引用本文的文献
1
Practical integrated healthcare prevention and management of children's health quality of respiratory functions: a systematic review.儿童呼吸功能健康质量的实用综合医疗保健预防与管理：一项系统综述
BMJ Public Health. 2025 Sep 4;3(2):e000477. doi: 10.1136/bmjph-2023-000477. eCollection 2025.
2
SARS-CoV-2 in Asthmatic Children: Same Consequences in Different Endotypes?哮喘儿童感染严重急性呼吸综合征冠状病毒2：不同内型会有相同后果吗？
Metabolites. 2025 Jun 16;15(6):406. doi: 10.3390/metabo15060406.
3
Histopathological examination of lung from infant with lethal COVID-19 with special attention on pneumocytes type II and the immune infiltrate: a case study.对患有致命性新冠病毒病的婴儿肺部进行组织病理学检查，特别关注II型肺细胞和免疫浸润：一项病例研究。
Ital J Pediatr. 2025 Jun 7;51(1):174. doi: 10.1186/s13052-025-01984-y.
4
Changes in metrics of continuous glucose monitoring during COVID-19 in Korean children and adolescents with type 1 diabetes mellitus.韩国1型糖尿病儿童和青少年在新冠疫情期间连续血糖监测指标的变化
Ann Pediatr Endocrinol Metab. 2025 Feb;30(1):38-44. doi: 10.6065/apem.2448036.018. Epub 2025 Feb 28.
5
SARS-CoV-2 Infections in a Triad of Primary School Learners (Grades 1-7), Their Parents, and Teachers in KwaZulu-Natal, South Africa: Protocol for a Cross-Sectional and Nested Case-Cohort Study.南非夸祖鲁-纳塔尔省小学一年级至七年级学生、家长和教师三人组中的新型冠状病毒2型感染：一项横断面和巢式病例队列研究方案
JMIR Res Protoc. 2024 Dec 19;13:e52713. doi: 10.2196/52713.
6
Dysbiosis of gut microbiota in COVID-19 is associated with intestinal DNA phage dynamics of lysogenic and lytic infection.新冠病毒感染（COVID-19）中肠道微生物群失调与溶原性和裂解性感染的肠道DNA噬菌体动态变化有关。
Microbiol Spectr. 2025 Jan 7;13(1):e0099824. doi: 10.1128/spectrum.00998-24. Epub 2024 Dec 10.
7
Patient-Centric Mobile Medical Services Accessed Through Smartphones in the Top 100 Chinese Public Hospitals: Cross-Sectional Survey Study.通过智能手机在中国百强公立医院获取的以患者为中心的移动医疗服务：横断面调查研究
JMIR Form Res. 2024 Dec 4;8:e45763. doi: 10.2196/45763.
8
Clinical, biochemical, and genetic study of TACE/TNF-α/ACE signaling pathway in pediatric COVID-19 infection.儿童新型冠状病毒肺炎感染中TACE/TNF-α/ACE信号通路的临床、生化及遗传学研究
Clin Exp Pediatr. 2024 Dec;67(12):704-717. doi: 10.3345/cep.2024.00941. Epub 2024 Nov 27.
9
Wastewater Surveillance of SARS-CoV-2: A Comparison of Two Concentration Methods.污水监测 SARS-CoV-2：两种浓缩方法的比较。
Viruses. 2024 Aug 31;16(9):1398. doi: 10.3390/v16091398.
10
Covid-19-induced pulmonary hypertension in children, and the use of phosphodiesterase-5 inhibitors.新冠病毒感染所致儿童肺动脉高压及磷酸二酯酶-5抑制剂的应用
F1000Res. 2022 Sep 12;10:792. doi: 10.12688/f1000research.53966.2. eCollection 2021.
Zotero 插件