• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

COVID-19 疫苗和免疫抑制的癌症患者:关键考虑因素。

COVID-19 Vaccines and Immunosuppressed Patients With Cancer: Critical Considerations.

机构信息

Memorial Sloan Kettering Cancer Center.

University of Arizona.

出版信息

Clin J Oncol Nurs. 2022 Jul 25;26(4):367-373. doi: 10.1188/22.CJON.367-373.

DOI:10.1188/22.CJON.367-373
PMID:35939727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9713690/
Abstract

BACKGROUND

 Patients with cancer are highly vulnerable to COVID-19 because of immunosuppression from diseases and treatments. Emerging data characterize the impact of COVID-19 vaccines related to cancer malignancies and treatments.

OBJECTIVES

 This article provides a clinical foundation on the immune response to the COVID-19 vaccine associated with the impact of cancer and its related treatments. It reviews strategies for vaccine scheduling, Centers for Disease Control and Prevention recommendations, and nursing considerations when administering the vaccine to immunosuppressed patients.

METHODS

 Research studies about immune responses to COVID-19 vaccines among immunosuppressed patients with hematologic and solid tumor malignancies were summarized.

FINDINGS

 Studies about the humoral immune responses of patients with cancer to COVID-19 vaccines help guide vaccination planning for this population. Critical nursing considerations for patients with cancer receiving COVID-19 vaccination are integral to the provision of optimal clinical oncology care during the pandemic.

摘要

背景

由于疾病和治疗导致的免疫抑制,癌症患者极易感染 COVID-19。新兴数据描述了 COVID-19 疫苗与癌症恶性肿瘤和治疗相关的影响。

目的

本文提供了与癌症及其相关治疗对 COVID-19 疫苗免疫反应相关的临床基础。本文综述了疫苗接种计划、疾病控制和预防中心推荐方案以及在为免疫抑制患者接种疫苗时的护理注意事项。

方法

总结了关于血液系统恶性肿瘤和实体瘤恶性肿瘤患者对 COVID-19 疫苗免疫反应的研究。

发现

癌症患者对 COVID-19 疫苗的体液免疫反应研究有助于指导该人群的疫苗接种计划。在大流行期间为接受 COVID-19 疫苗接种的癌症患者提供最佳临床肿瘤护理的关键护理注意事项是不可或缺的。

相似文献

1
COVID-19 Vaccines and Immunosuppressed Patients With Cancer: Critical Considerations.COVID-19 疫苗和免疫抑制的癌症患者:关键考虑因素。
Clin J Oncol Nurs. 2022 Jul 25;26(4):367-373. doi: 10.1188/22.CJON.367-373.
2
Administration of COVID-19 vaccines in immunocompromised patients.COVID-19 疫苗在免疫功能低下患者中的应用。
Int Immunopharmacol. 2021 Oct;99:108021. doi: 10.1016/j.intimp.2021.108021. Epub 2021 Jul 28.
3
Vaccines for preventing infections in adults with haematological malignancies.用于预防血液系统恶性肿瘤成人感染的疫苗。
Cochrane Database Syst Rev. 2025 May 21;5(5):CD015530. doi: 10.1002/14651858.CD015530.pub2.
4
COVID-19 Vaccination in Cancer Patients: A Review Article.新型冠状病毒肺炎(COVID-19)疫苗在癌症患者中的应用:一篇综述文章。
Cancer Control. 2022 Jan-Dec;29:10732748221106266. doi: 10.1177/10732748221106266.
5
Humoral Responses Against Variants of Concern by COVID-19 mRNA Vaccines in Immunocompromised Patients.免疫功能低下患者的 COVID-19 mRNA 疫苗针对关注变种的体液反应。
JAMA Oncol. 2022 May 1;8(5):e220446. doi: 10.1001/jamaoncol.2022.0446. Epub 2022 May 19.
6
Cowpox to COVID: History of vaccination in the immunocompromised host.牛痘到新冠:免疫功能低下宿主的疫苗接种史。
Transpl Infect Dis. 2023 Jun;25(3):e14051. doi: 10.1111/tid.14051. Epub 2023 Apr 7.
7
Cancer or COVID-19? A Review of Recommendations for COVID-19 Vaccination in Cancer Patients.癌症还是 COVID-19?癌症患者 COVID-19 疫苗接种建议的综述。
Curr Treat Options Oncol. 2021 Sep 13;22(10):95. doi: 10.1007/s11864-021-00903-7.
8
Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic.COVID-19、流感和肺炎球菌性肺炎疫苗接种在免疫抑制的免疫介导性炎症疾病成人中的接受障碍和促进因素:COVID-19 大流行期间的定性访谈研究。
PLoS One. 2022 Sep 9;17(9):e0267769. doi: 10.1371/journal.pone.0267769. eCollection 2022.
9
Shielding the immunocompromised: COVID-19 prevention strategies for patients with primary and secondary immunodeficiencies.保护免疫功能低下者:原发性和继发性免疫缺陷患者的新冠病毒预防策略
Vaccine. 2025 Apr 2;51:126853. doi: 10.1016/j.vaccine.2025.126853. Epub 2025 Feb 12.
10
COVID-19 vaccination in children and adolescents aged 5 years and older undergoing treatment for cancer and non-malignant haematological conditions: Australian and New Zealand Children's Haematology/Oncology Group consensus statement.5岁及以上正在接受癌症和非恶性血液疾病治疗的儿童及青少年的新冠病毒疫苗接种:澳大利亚和新西兰儿童血液学/肿瘤学组共识声明
Med J Aust. 2022 Apr 4;216(6):312-319. doi: 10.5694/mja2.51444. Epub 2022 Mar 10.

引用本文的文献

1
COVID-19-sensitive tumour response: 2-year assessment of the SARS-CoV-2 humoral response in cancer patients in oncology hospital in Poland.对COVID-19敏感的肿瘤反应:波兰肿瘤医院癌症患者中SARS-CoV-2体液反应的两年评估。
Cancer Immunol Immunother. 2024 Dec 21;74(1):27. doi: 10.1007/s00262-024-03895-z.
2
Factors Associated with Prolonged SARS-CoV-2 Viral Positivity in an Italian Cohort of Hospitalized Patients.意大利住院患者队列中与新冠病毒长期阳性相关的因素
Diseases. 2024 Jun 28;12(7):138. doi: 10.3390/diseases12070138.

本文引用的文献

1
Determinants of SARS-CoV-2 waning immunity in allogeneic hematopoietic stem cell transplant recipients.异体造血干细胞移植受者中 SARS-CoV-2 免疫衰减的决定因素。
J Hematol Oncol. 2022 Mar 18;15(1):27. doi: 10.1186/s13045-022-01250-2.
2
Humoral response to mRNA-based COVID-19 vaccine in patients with myeloid malignancies.mRNA 新冠疫苗在骨髓恶性肿瘤患者中的体液免疫反应。
Br J Haematol. 2022 Jun;197(6):691-696. doi: 10.1111/bjh.18138. Epub 2022 Mar 14.
3
Immunogenicity of COVID-19 mRNA vaccines in immunocompromised patients: a systematic review and meta-analysis.免疫功能低下患者的 COVID-19 mRNA 疫苗的免疫原性:系统评价和荟萃分析。
Eur J Med Res. 2022 Feb 12;27(1):23. doi: 10.1186/s40001-022-00648-5.
4
Antibody Response to SARS-CoV-2 Vaccination in Patients following Allogeneic Hematopoietic Cell Transplantation.异基因造血细胞移植后患者对 SARS-CoV-2 疫苗接种的抗体反应。
Transplant Cell Ther. 2022 Apr;28(4):214.e1-214.e11. doi: 10.1016/j.jtct.2022.01.019. Epub 2022 Jan 31.
5
Learning through a Pandemic: The Current State of Knowledge on COVID-19 and Cancer.通过疫情学习:关于 COVID-19 和癌症的现有知识状况。
Cancer Discov. 2022 Feb;12(2):303-330. doi: 10.1158/2159-8290.CD-21-1368. Epub 2021 Dec 10.
6
Efficacy of a third BNT162b2 mRNA COVID-19 vaccine dose in patients with CLL who failed standard 2-dose vaccination.三剂 BNT162b2 mRNA COVID-19 疫苗在标准两剂接种失败的 CLL 患者中的疗效。
Blood. 2022 Feb 3;139(5):678-685. doi: 10.1182/blood.2021014085.
7
Disease- and Therapy-Specific Impact on Humoral Immune Responses to COVID-19 Vaccination in Hematologic Malignancies.血液恶性肿瘤患者中疾病和治疗特异性对 COVID-19 疫苗接种后体液免疫应答的影响。
Blood Cancer Discov. 2021 Sep 13;2(6):568-576. doi: 10.1158/2643-3230.BCD-21-0139. eCollection 2021 Nov.
8
COVID-19 vaccination in patients with breast cancer and gynecological malignancies: A German perspective.COVID-19 疫苗接种在乳腺癌和妇科恶性肿瘤患者中的应用:德国视角。
Breast. 2021 Dec;60:214-222. doi: 10.1016/j.breast.2021.10.012. Epub 2021 Oct 29.
9
Effectiveness of 2-Dose Vaccination with mRNA COVID-19 Vaccines Against COVID-19-Associated Hospitalizations Among Immunocompromised Adults - Nine States, January-September 2021.mRNA 新冠疫苗 2 剂接种对免疫功能低下成人因 COVID-19 住院的效果-9 个州,2021 年 1 月至 9 月。
MMWR Morb Mortal Wkly Rep. 2021 Nov 5;70(44):1553-1559. doi: 10.15585/mmwr.mm7044e3.
10
Evaluation of COVID-19 Mortality and Adverse Outcomes in US Patients With or Without Cancer.评估有或无癌症的美国 COVID-19 患者的死亡率和不良结局。
JAMA Oncol. 2022 Jan 1;8(1):69-78. doi: 10.1001/jamaoncol.2021.5148.