Department of Orthopedics and Trauma surgery, Fracture Liaison Service, Reinier de Graaf Hospital, Delft, The Netherlands.
Department of Medical Laboratories, Association of Clinical Chemistry, Reinier the Graaf Hospital, Delft, The Netherlands.
Osteoporos Int. 2020 Oct;31(10):2007-2015. doi: 10.1007/s00198-020-05442-9. Epub 2020 May 13.
This study aimed to gain insight in specific characteristics and beliefs of FLS non-responders.
The proportion of non-responding fracture liaison service (FLS) invitees is high but characteristics of FLS non-responders are unknown.
We contacted FLS non-responders by telephone to consent with home visit (HV) and to fill in a questionnaire or, if HV was refused, to receive a questionnaire by post (Q), to gain insight in beliefs on fracture cause and subsequent fracture risk.
Out of 716 FLS invitees, 510 attended, nine declined, and 197 did not respond. Of these non-responders, 181 patients were consecutively traced and phoned until 50 consented with HV. Forty-two declined HV but consented with Q. Excluded were eight Q-consenters in whom no choice was offered (either HV or Q) and 81 patients who declined any proposition (non-HV|Q). 62% HV and Q could recall the FLS invitation letter. The fracture cause was differently believed between HV and Q; the fall (96% versus 79%, p = .02), bad physical condition (36% versus 2%, p = .0001), dizziness or imbalance (24% versus Q 7%, p = .03), osteoporosis (16% versus 2%, p = .02), and increased fracture risk (26% versus 17%, NS). Age ≥ 70, woman, and major fracture were significantly associated with HV consent compared to Q (OR 2.7, 2.5, and 2.4, respectively) and HV compared to non-HV|Q (OR 16.8, 5.3, and 6.1).
FLS non-responders consider fracture risk as low. Note, 50 patients (about 25%) consented with a home visit after one telephone call, mainly older women with a major fracture. This non-responder subgroup with high subsequent fracture risk is therefore approachable for secondary fracture prevention.
了解脆性骨折联络服务(FLS)未响应者的特定特征和信念。
FLS 邀请未响应者的比例较高,但 FLS 未响应者的特征尚不清楚。
我们通过电话联系 FLS 未响应者,同意进行家访(HV)并填写问卷,或者如果拒绝 HV,则通过邮寄(Q)接收问卷,以了解对骨折原因和随后骨折风险的信念。
在 716 名 FLS 邀请者中,有 510 人出席,9 人拒绝,197 人未回复。在这些未响应者中,连续追踪了 181 名患者并打电话,直到 50 名同意 HV。42 人拒绝 HV,但同意 Q。排除了 8 名 Q 同意者,他们没有选择 HV 或 Q,还有 81 名拒绝任何提议(非 HV|Q)的患者。62% HV 和 Q 可以回忆起 FLS 邀请信。HV 和 Q 对骨折原因的看法不同;跌倒(96%对 79%,p=0.02)、身体状况不佳(36%对 2%,p=0.0001)、头晕或失衡(24%对 Q 7%,p=0.03)、骨质疏松症(16%对 2%,p=0.02)和骨折风险增加(26%对 17%,NS)。与 Q 相比,年龄≥70 岁、女性和主要骨折与 HV 同意显著相关(OR 2.7、2.5 和 2.4),与非 HV|Q 相比,HV 也显著相关(OR 16.8、5.3 和 6.1)。
FLS 未响应者认为骨折风险较低。请注意,在一次电话后,有 50 名患者(约 25%)同意进行家访,主要是年龄较大的女性有主要骨折。因此,这个具有高后续骨折风险的未响应者亚组可以接受二级骨折预防。