Population Health and Disease Prevention and the Chao Family Comprehensive Cancer Center, University of California Irvine, 653 E Peltason Drive, Irvine, CA, 95697-3957, USA.
Interdisciplinary Institute for Salivary Bioscience Research, University of California Irvine, Irvine, CA, USA.
Int J Behav Med. 2020 Jun;27(3):257-261. doi: 10.1007/s12529-020-09900-w.
Behavioral medicine research from across the globe has been catalyzed by the quest to understand the interactions between psychological, social, and physiological factors underlying disparities in human health. A more complete biopsychosocial model increasingly integrates advanced clinical and laboratory assessments of relevant environmental chemicals, biological mediators of inflammation, cardiometabolic and endocrine markers, infectious disease exposure, and genetic polymorphisms determined from saliva specimens. The overarching aims are to identify mechanisms, decode moderating processes that translate adversity into risk, and verify the impact of clinical intervention. This special issue of the International Journal of Behavioral Medicine highlights novel contributions of salivary bioscience with emphasis on research utilizing varied research designs (i.e., experimental, longitudinal, dyadic), incorporating a broad array of salivary analytes, and investigating the influence of psychological and social factors on human health.
全球行为医学研究一直致力于了解人类健康差异背后的心理、社会和生理因素之间的相互作用。一个更加完整的生物心理社会模型越来越多地整合了对相关环境化学物质、炎症的生物介质、心血管代谢和内分泌标志物、传染病暴露以及从唾液样本中确定的遗传多态性的先进临床和实验室评估。首要目标是确定机制，解码将逆境转化为风险的调节过程，并验证临床干预的效果。《国际行为医学杂志》的这个特刊重点介绍了唾液生物科学的新贡献，强调利用各种研究设计（即实验、纵向、对偶）、纳入广泛的唾液分析物以及研究心理和社会因素对人类健康的影响的研究。
