College of Humanities & Science, Thomas Jefferson University, 4201 Henry Avenue, Philadelphia, PA, 19144, USA.
Section on Behavioral Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Int J Behav Med. 2020 Jun;27(3):294-304. doi: 10.1007/s12529-019-09820-4.
The sex hormone estradiol, as measured through saliva, represents a non-invasive and cost-effective approach to understanding the influence of hormonal factors on physical and psychological well-being among women. Estradiol levels dramatically change at hormonal transitions, such as puberty, menopause, and postpartum. It is at these transitions where women are at increased risk for psychological and somatic distress. Salivary estradiol also has implications for decision-making and has been broadly associated with engagement in health-compromising behaviors which can influence women's ability to cope with and manage chronic health conditions. This review summarizes the evidence for salivary estradiol as a marker of physical and psychological health, and discusses practical information regarding saliva collection and assay. The overall intent is to expand and clarify knowledge of the relation between changes in salivary estradiol and women's health as well as to provide a means of integrating salivary estradiol into future behavioral medicine research.
唾液中的性激素雌二醇是一种非侵入性且具有成本效益的方法，可以了解激素因素对女性身心健康的影响。雌二醇水平在激素转变期间（如青春期、绝经期和产后）会急剧变化。在这些转变期间，女性面临心理和躯体困扰的风险增加。唾液中的雌二醇也与决策有关，并与广泛参与危害健康的行为有关，这些行为会影响女性应对和管理慢性健康状况的能力。本综述总结了唾液雌二醇作为身体和心理健康标志物的证据，并讨论了有关唾液收集和分析的实用信息。总体目的是扩展和阐明唾液雌二醇与女性健康之间的关系，并提供一种将唾液雌二醇纳入未来行为医学研究的方法。
