McArdle F J, Brown B H, Pearse R G, Barber D C
Sheffield University, Department of Medical Physics and Clinical Engineering, Royal Hallamshire Hospital, UK.
Clin Phys Physiol Meas. 1988;9 Suppl A:55-60. doi: 10.1088/0143-0815/9/4a/010.
An investigation is presented into the likely effects of the neonatal skull on impedance images produced by applied potential tomography (APT) by imaging impedance changes inside the skull of a human infant of occipito-frontal circumference 30 cm. Measurements have been made with the skull immersed in a tank of saline and electrodes fixed to the perimeter of the tank. Sensitivity measurements have been assessed for imaging a small target close to the centre of the skull as compared with images produced without the skull. The results obtained compare favourably with measurements on a more realistic model of the neonatal head constructed by filling the skull with agar jelly to leave only a thin exterior coating of jelly to simulate the scalp. These experiments suggest that in the central region of the head of a neonate, measured changes by the APT technique are about 44% of that expected from a homogeneous phantom, but that this might vary from 32% to 55% at different points in the image in a very complex manner.
本文通过对一名枕额周长为30厘米的人类婴儿颅骨内部的阻抗变化进行成像，研究了新生儿颅骨对应用电位断层扫描（APT）产生的阻抗图像的可能影响。测量是在颅骨浸入盐水槽且电极固定在水槽周边的情况下进行的。与无颅骨时产生的图像相比，评估了对靠近颅骨中心的小目标成像的灵敏度测量。所获得的结果与在更逼真的新生儿头部模型上的测量结果相比具有优势，该模型是通过用琼脂冻填充颅骨，仅留下一层薄的外部冻层来模拟头皮构建的。这些实验表明，在新生儿头部的中心区域，APT技术测量的变化约为均匀体模预期变化的44%，但在图像中的不同点，这一比例可能以非常复杂的方式在32%至55%之间变化。
