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四电极阻抗技术:一种用于研究管腔器官顺应性的方法。

The four-electrode impedance technique: a method for investigation of compliance in luminal organs.

作者信息

Gregersen H, Stodkilde-Jorgensen H, Djurhuus J C, Mortensen S O

机构信息

Institute of Experimental Clinical Research, University of Aarhus, Denmark.

出版信息

Clin Phys Physiol Meas. 1988;9 Suppl A:61-4. doi: 10.1088/0143-0815/9/4a/011.

DOI:10.1088/0143-0815/9/4a/011
PMID:3240652
Abstract

A probe for measurement of related values of cross-sectional area (CA) and pressure has been developed to record characteristics of the walls in luminal organs. The aim of this study was to test the probe in vitro. CA was measured in the range 0.17 to 7.07 cm2 by means of the field gradient principle. Pressure was measured in the range 0 to 20 kPa (150 mmHg) by external transducers. After calibration both the pressure and the CA measuring system did measure the parameters adequately. The CA measuring system was dependent on the temperature and electrolyte concentration of the fluid, but was not affected by the size and form outside the excitation electrodes. The upper frequency limits for recordings of CA and pressure were 15.7 and 0.44 Hz, respectively. These in vitro results indicate that the tube assembly has characteristics sufficient for simultaneous measurement of CA and pressure in sphincter regions. These two variables can be used to describe mechanical wall properties such as compliance, hysteresis and creep.

摘要

已开发出一种用于测量横截面积(CA)和压力相关值的探头,以记录腔道器官壁的特征。本研究的目的是在体外测试该探头。通过场梯度原理在0.17至7.07平方厘米的范围内测量CA。通过外部传感器在0至20 kPa(150 mmHg)的范围内测量压力。校准后,压力和CA测量系统均能充分测量参数。CA测量系统取决于流体的温度和电解质浓度,但不受激励电极外部尺寸和形状的影响。CA和压力记录的上限频率分别为15.7和0.44 Hz。这些体外结果表明,该管组件具有足以同时测量括约肌区域CA和压力的特性。这两个变量可用于描述机械壁特性,如顺应性、滞后和蠕变。

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