从银莲花中分离得到的两个新木脂素的结构阐明及其抗炎活性。
Structure Elucidation of Two New Norlignans from Anemone vitifolia and Their Anti-Inflammatory Activities.
机构信息
Department of Ecology, School of Life Sciences, Nanjing University, Nanjing, 210046, P. R. China.
State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, P. R. China.
出版信息
Chem Biodivers. 2020 Jul;17(7):e2000184. doi: 10.1002/cbdv.202000184. Epub 2020 Jun 23.
Two new norlignans together with two known phenylpropanoids were isolated from the whole herb of Anemone vitifolia. All compounds were reported from this plant for the first time. The structures of these compounds were identified by comprehensive HR-ESI-MS, 1D and 2D NMR spectroscopic data analysis and comparison with literature data. Additionally, bioactivity study results showed that two new compounds have potential anti-inflammatory activity. The plausible biosynthetic pathway for these compounds were also speculated in this article.
从茴芹属植物全草中分离得到两个新的木脂素和两个已知的苯丙素类化合物。这些化合物均为首次从该植物中分离得到。通过高分辨电喷雾电离质谱（HR-ESI-MS）、一维和二维核磁共振（NMR）波谱数据分析，并与文献数据进行比较，鉴定了这些化合物的结构。此外，生物活性研究结果表明，两个新化合物具有潜在的抗炎活性。本文还推测了这些化合物的可能生物合成途径。
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