Körner T, Rath F W, Schmidt H
Martin Luther University Halle, Wittenberg.
Exp Pathol. 1988;35(4):247-51. doi: 10.1016/s0232-1513(88)80095-1.
Cultivated skin fibroblasts were fed with retinol palmitate in a dosage of 100,000, 200,000, or 300,000 I.U. In dependence on the dosage a remarkable uptake and storage of vitamin A can be observed in vitro (27.2, 53.0 or 60.7% of the fibroblasts). Distinctly retinol palmitate storing cells have lost their typical fibroblast-like appearance and are transformed into cells which are comparable to the Ito cells of the liver from the cytomorphological point of view.
用剂量为100,000、200,000或300,000国际单位的视黄醇棕榈酸酯培养皮肤成纤维细胞。根据剂量不同，在体外可观察到维生素A有显著的摄取和储存（占成纤维细胞的27.2%、53.0%或60.7%）。明显储存视黄醇棕榈酸酯的细胞已失去其典型的成纤维细胞样外观，从细胞形态学角度来看，转变为与肝脏的伊托细胞类似的细胞。
