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促进器官修复和再生的新靶点和治疗策略。

Novel Targets and Therapeutic Strategies for Promoting Organ Repair and Regeneration.

机构信息

Department of Developmental Biology, Harvard School of Dental Medicine, Harvard University, 188 Longwood Avenue, Boston, MA 02115, USA.

Department of Pharmacology, Dalhousie University, 1348 Summer street, North tower 3rd floor, Halifax, NS B3H 4R2, Canada.

出版信息

Biomolecules. 2020 May 12;10(5):749. doi: 10.3390/biom10050749.

Abstract

Strategies to create functional organs and tissues is of great interest for use in regenerative medicine in order to repair or replace the lost tissues due to injury, disease, as well as aging. Several new treatment options, including stem cell treatments and tissue-engineered substitutes for certain indications, have been approved by Food and Drug Administration (FDA) and are currently available. This special issue will cover new therapies and strategies that are currently being investigated under preclinical and clinical settings.

摘要

为了修复或替换因损伤、疾病和衰老而导致的组织缺失,创造具有功能性的器官和组织的策略在再生医学领域具有重要的应用价值。包括干细胞疗法和针对某些适应症的组织工程替代物在内的几种新的治疗选择已获得美国食品和药物管理局(FDA)的批准,目前已上市。本期特刊将涵盖目前正在临床前和临床研究中的新疗法和策略。

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