Alford Chris, Broom Callum, Carver Harriet, Johnson Sean J, Lands Sam, Reece Rebecca, Verster Joris C
University of the West of England, Bristol BS16 1QY, UK.
Centre for Trials Research, Cardiff University, Cardiff CF14 4YS, UK.
J Clin Med. 2020 May 12;9(5):1435. doi: 10.3390/jcm9051435.
Driving is increasing across the world and road traffic accidents are a major cause of serious injuries and fatalities. The link between alcohol consumption and impaired driving has long been established and has led to legislation in many countries, with enforcement of legal limits based on blood alcohol concentration levels. Alcohol hangover research is an emerging field with a range of laboratory and naturalistic studies now clearly demonstrating the significant impairments that can result from hangover, even when alcohol levels are measured at or close to zero the day following a social drinking occasion. Driving is a commonplace activity but requires competency with a range of complex and potentially demanding tasks. Driving impaired can have serious consequences, including death and serious injury. There have been only limited alcohol hangover driving studies. The studies presented examined the consequences of alcohol hangover with a driving simulator contrasting a group with zero residual alcohol (N = 26) next day and another with residual alcohol (N = 26) assessed with breathalyzer in the morning before undertaking a 20 min commute to work. All participants completed a morning drive after a night without alcohol consumption and another after a night of social drinking. The driving scenarios were relatively demanding including traffic and pedestrians, traffic lights and other potential hazards in a mixed rural and urban journey. Subjective hangover and workload were assessed in addition to a range of driving performance variables, including divided attention, steering control and driving violations. Analyses contrasted driving in the no alcohol condition with the residual alcohol condition. The combined groups data (N = 52) was contrasted with the zero and residual alcohol groups. Significant contrasts were found for a range of driving measures, including divided attention, vehicle control, and driving violations as well as perceived workload. The pattern of impairment was broadly similar across both groups, indicating that whether or not residual alcohol was present, consistent driving impairment was seen. The relatively high number of significant variables may reflect the increased cognitive demand of the 20 min commute drive including busy and complex urban environments. This was also reflected in the significant increase in perceived workload recorded across the 6 dimensions of the National Aeronautics and Space Administration Task Load Index (NASA-TLX). Associations between subjective measures and driving performance with hangover suggested a potential lack of awareness of impairment, though were limited in number. The overall findings indicate that the levels of impairment seen reflect those seen with alcohol impaired driving, even when breath alcohol is zero.
在全球范围内,驾车行为日益增多,道路交通事故是导致严重受伤和死亡的主要原因。饮酒与驾驶能力受损之间的关联早已确立,这促使许多国家制定了相关法律,依据血液酒精浓度水平来执行法定限制。酒精宿醉研究是一个新兴领域,一系列实验室研究和自然观察研究现已清楚表明,宿醉会导致严重的功能损害,即便在社交饮酒后的次日测得酒精含量为零或接近零。驾驶是一项常见活动,但需要具备完成一系列复杂且可能要求较高任务的能力。驾驶能力受损可能会造成严重后果,包括死亡和重伤。关于酒精宿醉对驾驶影响的研究数量有限。所呈现的这些研究使用驾驶模拟器,对比了次日残余酒精含量为零的一组(N = 26)和另一组在上班通勤20分钟前经呼气酒精含量测定仪检测有残余酒精的一组(N = 26),以此来探究酒精宿醉的后果。所有参与者分别在未饮酒的一晚后和社交饮酒的一晚后完成了一次晨间驾驶。驾驶场景要求相对较高,包括在城乡混合路段中应对交通和行人、交通信号灯以及其他潜在危险。除了一系列驾驶性能变量,如注意力分散、转向控制和驾驶违规行为外,还评估了主观宿醉感受和工作量。分析对比了无酒精状态下的驾驶情况和有残余酒精状态下的驾驶情况。将两组数据合并(N = 52)后与残余酒精含量为零的组和有残余酒精的组进行对比。在一系列驾驶指标上发现了显著差异,包括注意力分散、车辆控制、驾驶违规行为以及感知到的工作量。两组的损害模式大致相似,这表明无论是否存在残余酒精,都会出现持续的驾驶能力损害。相对较多的显著变量可能反映出20分钟通勤驾驶(包括繁忙且复杂的城市环境)对认知能力的需求增加。这也反映在美国国家航空航天局任务负荷指数(NASA - TLX)的6个维度上记录的感知工作量显著增加。主观测量指标与宿醉状态下驾驶性能之间的关联表明,尽管数量有限,但可能存在对驾驶能力受损缺乏认知的情况。总体研究结果表明,即便呼气酒精含量为零,所观察到的损害程度与酒后驾驶时的损害程度相当。