School of Stomatology, Nanchang University, Nanchang 330006, China; The Key Laboratory of Oral Biomedicine, Jiangxi Province, Nanchang 330006, China.
College of Chemistry, Nanchang University, Nanchang 330031, China.
Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110887. doi: 10.1016/j.msec.2020.110887. Epub 2020 Mar 21.
Carbon nanotube (CNT) has aroused much attention in biomedical field. However, the cytotoxicity and aggregation are critical factors that affect the application of carbon nanotube (CNT). Herein, gelatin was grafted on the surface of CNT via mussel-inspired method. The gelatin modified CNT can disperse homogeneously in water. The in vitro test showed that gelatin modified CNT showed much better biocompatibility than the native CNT, which may improve its potential application in biomedical field.
碳纳米管（CNT）在生物医学领域引起了广泛关注。然而，细胞毒性和聚集性是影响碳纳米管（CNT）应用的关键因素。本研究通过贻贝启发的方法在 CNT 表面接枝明胶。明胶修饰的 CNT 可以均匀分散在水中。体外实验表明，明胶修饰的 CNT 比原 CNT 具有更好的生物相容性，这可能提高其在生物医学领域的潜在应用。
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