Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, Deemed to be University, Bhubaneswar, Odisha, India.
School of Life Sciences, Sambalpur University, Odisha, India.
Arch Med Res. 2020 Jul;51(5):363-374. doi: 10.1016/j.arcmed.2020.04.020. Epub 2020 Apr 30.
The recent outbreak of CoVID-19 is declared as a global public health emergency of international concern by the World Health Organization (WHO). A fresh figure of 2268011 positive cases and 155185 death records (till April 18 2020) across the worldwide signify the severity of this viral infection. CoVID-19 infection is a pandemic, surface to surface communicable disease with a case fatality rate of 3.4% as estimated by WHO up to March 3 2020. Unfortunately, the current unavailability of an effective antiviral drug and approved vaccine, worsen the situation more critical. Implementation of an effective preventive measure is the only option left to counteract CoVID-19. Further, a retrospective analysis provides evidence that contemplates the decisive role of preventive measures in controlling severe acute respiratory syndrome (SARS) outbreak in 2003. A statistical surveillance report of WHO reflects, maintaining a coherent infection, prevention and control guideline resulted in a 30% reduction in healthcare-associated infections. The effectiveness of preventive measures completely relies on the strength of surface disinfectants, the composition of hand sanitizer, appropriate material for the manufacture of personal protective equipment (PPE). This review enlightens the various preventive measures such as a suitable selection of surface disinfectants, appropriate hand sanitization, and empowering the PPE that could be a potential intervention to fight against CoVID-19.
最近爆发的 CoVID-19 被世界卫生组织(WHO)宣布为国际关注的全球公共卫生紧急事件。截至 2020 年 4 月 18 日,全球范围内已有 2268011 例阳性病例和 155185 例死亡记录,这表明了这种病毒感染的严重性。CoVID-19 感染是一种全球性的、表面传播的传染病,据世界卫生组织估计,截至 2020 年 3 月 3 日的病死率为 3.4%。不幸的是,目前尚无有效的抗病毒药物和批准的疫苗,这使得情况更加危急。实施有效的预防措施是对抗 CoVID-19 的唯一选择。此外,回顾性分析提供的证据表明,预防措施在控制 2003 年严重急性呼吸系统综合征(SARS)爆发方面发挥了决定性作用。世界卫生组织的统计监测报告反映,坚持一致的感染、预防和控制准则可使与医疗保健相关的感染减少 30%。预防措施的有效性完全取决于表面消毒剂的强度、洗手液的成分、个人防护设备(PPE)的制造材料。本综述阐明了各种预防措施,如选择合适的表面消毒剂、适当的手部消毒以及增强 PPE 等,这些措施可能是对抗 CoVID-19 的潜在干预措施。