Chin Pei-Ju, La Neve Fabio, Zanda Valeria, Khan Arifa S
Laboratory of Retroviruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Istituto di Ricerche Biomediche A. Marxer, Merck, Colleretto Giacosa, Italy.
Microbiol Resour Announc. 2020 May 14;9(20):e00233-20. doi: 10.1128/MRA.00233-20.
This full-length genome sequence of a feline leukemia virus Kawakami-Theilen strain (designated KT-FeLV-UCD-1), produced from the chronically infected FL74-UCD-1 cell line, was obtained using high-throughput sequencing. It consisted of 8,464 bp and had a genomic organization similar to that of other gammaretroviruses, containing long terminal repeats and open reading frames for Gag, Pol, and Env.
利用高通量测序技术获得了一株由长期感染的FL74-UCD-1细胞系产生的猫白血病病毒川上-蒂伦毒株(命名为KT-FeLV-UCD-1)的全长基因组序列。该序列由8464个碱基对组成,其基因组结构与其他γ逆转录病毒相似,包含长末端重复序列以及Gag、Pol和Env的开放阅读框。