Medical and Preventive Services Branch, Fulton County Board of Health, 10 Park Place South SE, Atlanta, GA, 30303, USA.
Division of Infectious Disease, School of Medicine, Emory University, Atlanta, GA, USA.
Arch Sex Behav. 2020 Aug;49(6):2193-2204. doi: 10.1007/s10508-020-01711-0. Epub 2020 May 14.
Assessing pre-exposure prophylaxis (PrEP) coverage and identifying reasons for disproportionate uptake among the varied social and cultural sub-groups of men who have sex with men (MSM) and transgender women who have sex with men (TWSM) are necessary precursors to setting attainable local PrEP. We report on findings of a cross-sectional survey among MSM/TWSM attending Gay pride events in Atlanta, Georgia, in 2018. Associations between PrEP awareness, uptake, and respondent characteristics were assessed using logistic regression. PrEP awareness did not differ by race, but current use was significantly lower among Blacks at substantial risk of HIV (p = .008). In multivariate analysis, clinician encounter in the past year was associated with awareness while age, income, drug use, sero-discordant sex, and multiple male partners were associated with current use. Among PrEP-naïve MSM/TWSM, the most common reasons for nonuse differed by race (poor knowledge of PrEP: Black-45% vs. non-Black-27%, p = .010, low perception of risk: Black-26% vs. non-Black-52%, p = .001). Key racial and socioeconomic disparities in active PrEP use and reasons for nonuse remain despite the recent increases in PrEP awareness and use among MSM/TWSM in Atlanta. Achieving overall improvement in uptake among all MSM/TWSM sub-groups will require tailoring PrEP educational messaging, optimizing communication modalities, expanding provider outreach, and identifying ways to defray costs for high-risk, underserved sub-groups in these populations.
评估男男性行为者(MSM)和跨性别女性与男性发生性行为者(TWSM)中不同社会文化亚群的暴露前预防(PrEP)覆盖情况,并确定其不成比例接受 PrEP 的原因,这对于制定可实现的当地 PrEP 计划是必要的前提。我们报告了 2018 年在佐治亚州亚特兰大举行的同性恋骄傲活动中参加的 MSM/TWSM 横断面调查的结果。使用逻辑回归评估 PrEP 意识、接受度和受访者特征之间的关联。PrEP 意识不因种族而异,但在面临重大 HIV 风险的黑人中,目前的使用率明显较低(p = 0.008)。在多变量分析中,过去一年中的临床医生接触与意识相关,而年龄、收入、吸毒、血清不一致的性行为和多个男性伴侣与当前使用相关。在 PrEP 初治的 MSM/TWSM 中,未使用 PrEP 的最常见原因因种族而异(对 PrEP 的了解不足:黑人 45%,非黑人 27%,p = 0.010,对风险的认知不足:黑人 26%,非黑人 52%,p = 0.001)。尽管最近亚特兰大 MSM/TWSM 中 PrEP 的意识和使用率有所增加,但活跃 PrEP 使用和未使用的关键种族和社会经济差异仍然存在。要提高所有 MSM/TWSM 亚群的总体接受度,就需要调整 PrEP 教育信息,优化沟通方式,扩大提供者的外联范围,并寻找为这些人群中高风险、服务不足的亚群降低成本的方法。