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胫骨聚乙烯部件的后侧磨损受步态模式的影响:使用稀土示踪技术的膝关节模拟器研究。

Backside wear of tibial polyethylene components is affected by gait pattern: A knee simulator study using rare earth tracer technology.

机构信息

Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.

Central Laboratory of Analytical Chemistry, Hamburg University of Technology, Hamburg, Germany.

出版信息

J Orthop Res. 2020 Jul;38(7):1607-1616. doi: 10.1002/jor.24720. Epub 2020 May 25.

Abstract

The aim of this study was to determine the effect of two in-vivo-determined gait patterns, one with low and one with high anteroposterior (AP) motion, on total and backside polyethylene insert wear in comparison with the ISO (International Organization for Standardization) standard 14243-3. In order to differentiate and accurately quantify topside and backside wear, a novel technique was employed where different lanthanide tracers were incorporated into the polyethylene during manufacture. Wear particle analysis was conducted following established protocols. For all tested liners and motion protocols, the chemically calculated wear rates correlated closely with gravimetrically determined wear. Both in vivo motion groups displayed higher wear rates than the ISO group following the order of the AP motion amplitudes. Backside wear for ISO constituted 2.76% ± 0.90% (mean ± SE) of the total wear, increasing significantly to 15.8% ± 3.2% for the low AP and further increasing to 19.3% ± 0.95% for the high AP motion protocol. The mean wear particle sizes were under 200 nm for all three motion patterns, being largest for the protocol with high AP motion. Particle release from the low and high AP gait patterns was 1.9 to 2.8 times that from the ISO protocol. Testing for the proportion of backside wear across various activities of daily living should be an important consideration in evaluating knee prostheses wear.

摘要

本研究旨在确定两种体内确定的步态模式(一种具有低前后向(AP)运动,另一种具有高 AP 运动)对总聚乙烯插入物磨损和后聚乙烯插入物磨损的影响,并与 ISO(国际标准化组织)标准 14243-3 进行比较。为了区分和准确量化顶面和底面磨损,采用了一种新的技术,即在制造过程中向聚乙烯中掺入不同的镧系元素示踪剂。按照既定方案进行了磨损颗粒分析。对于所有测试的衬垫和运动方案,化学计算的磨损率与重量法确定的磨损率密切相关。在所有测试的衬垫和运动方案中,与 ISO 组相比,体内运动组的磨损率更高,其顺序为 AP 运动幅度。ISO 的后聚乙烯插入物磨损占总磨损的 2.76%±0.90%(平均值±SE),对于低 AP 运动协议显著增加到 15.8%±3.2%,对于高 AP 运动协议进一步增加到 19.3%±0.95%。对于所有三种运动模式,平均磨损颗粒尺寸均小于 200nm,对于具有高 AP 运动的协议最大。从低和高 AP 步态模式释放的磨损颗粒是 ISO 方案的 1.9 到 2.8 倍。评估膝关节假体磨损时,应考虑日常生活中各种活动的后聚乙烯插入物磨损比例。

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