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卡梅伦溃疡:酒精使用障碍患者发生明显上消化道出血的罕见病例。

Cameron Ulcers: Rare Case of Overt Upper Gastrointestinal Bleed in a Patient with Alcohol Use Disorder.

作者信息

Mehershahi Shehriyar, Jog Abhishrut, Ronderos Diana M, Shaikh Danial, Ihimoyan Ariyo

机构信息

Gastroenterology, BronxCare Health System, Bronx, USA.

Internal Medicine, BronxCare Health System, Bronx, USA.

出版信息

Cureus. 2020 Apr 12;12(4):e7644. doi: 10.7759/cureus.7644.

DOI:10.7759/cureus.7644
PMID:32411546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7217238/
Abstract

Cameron lesion is an uncommon cause of overt upper gastrointestinal bleed (GI bleed). Though hiatal hernia is a well-known entity, Cameron lesions that may occur in them are usually missed during upper endoscopy. Patient with Cameron lesions usually presents as chronic iron deficiency anemia, rarely as acute GI bleed. Multiple other risk factors such as non-steroidal anti-inflammatory drug use, alcohol consumption, gastro-esophageal reflux disease (GERD) may be present concomitantly which makes initial differential diagnosis of Cameron lesions more difficult as seen in our case.

摘要

卡梅伦病变是明显的上消化道出血(GI出血)的罕见原因。虽然食管裂孔疝是一个众所周知的病症,但其中可能出现的卡梅伦病变在上消化道内镜检查时通常会被漏诊。患有卡梅伦病变的患者通常表现为慢性缺铁性贫血,很少表现为急性GI出血。可能同时存在多种其他风险因素,如使用非甾体抗炎药、饮酒、胃食管反流病(GERD),这使得卡梅伦病变的初步鉴别诊断更加困难,如我们病例中所见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bad/7217238/826ec734d2c8/cureus-0012-00000007644-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bad/7217238/826ec734d2c8/cureus-0012-00000007644-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bad/7217238/826ec734d2c8/cureus-0012-00000007644-i01.jpg

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本文引用的文献

1
Endoscopic management of nonvariceal, nonulcer upper gastrointestinal bleeding.非静脉曲张性、非溃疡性上消化道出血的内镜治疗
Gastroenterol Clin North Am. 2014 Dec;43(4):707-19. doi: 10.1016/j.gtc.2014.08.004. Epub 2014 Sep 12.
2
Cameron lesions in patients with hiatal hernias: prevalence, presentation, and treatment outcome.食管裂孔疝患者的卡梅伦病变:患病率、表现及治疗结果。
Dis Esophagus. 2015 Jul;28(5):448-52. doi: 10.1111/dote.12223. Epub 2014 Apr 24.
3
Severe upper gastrointestinal hemorrhage from linear gastric ulcers in large hiatal hernias: a large prospective case series of Cameron ulcers.
巨大食管裂孔疝中线性胃溃疡导致的重度上消化道出血:卡梅隆溃疡的大型前瞻性病例系列。
Endoscopy. 2013;45(5):397-400. doi: 10.1055/s-0032-1326294. Epub 2013 Apr 24.
4
Cameron ulcers: an atypical source for a massive upper gastrointestinal bleed.卡梅隆溃疡:上消化道大出血的非典型病因。
World J Gastroenterol. 2012 Sep 21;18(35):4959-61. doi: 10.3748/wjg.v18.i35.4959.
5
Cameron ulcers: you will find only what you seek.卡梅伦溃疡:你只会找到你所寻找的东西。
Dig Dis Sci. 2011 Dec;56(12):3450-2. doi: 10.1007/s10620-011-1803-y. Epub 2011 Jun 25.
6
Cameron lesions: unusual cause of gastrointestinal bleeding and anemia.卡梅伦病变:胃肠道出血和贫血的罕见病因。
Digestion. 2008;77(3-4):214-7. doi: 10.1159/000144281. Epub 2008 Jul 12.
7
Endoscopic difficulties in the diagnosis of upper gastrointestinal bleeding.上消化道出血诊断中的内镜检查难点
World J Gastroenterol. 2001 Jun;7(3):308-12. doi: 10.3748/wjg.v7.i3.308.
8
Endoscopic treatment of a Cameron lesion presenting as life-threatening gastrointestinal hemorrhage.内镜治疗表现为危及生命的胃肠道出血的卡梅伦病变。
J Clin Gastroenterol. 2001 Nov-Dec;33(5):423-4. doi: 10.1097/00004836-200111000-00018.
9
Diagnostic and therapeutic impact of push enteroscopy: analysis of factors associated with positive findings.推进式小肠镜检查的诊断和治疗影响:与阳性结果相关因素的分析
Gastrointest Endosc. 1998 Jan;47(1):18-22. doi: 10.1016/s0016-5107(98)70293-7.
10
Hiatal hernia with cameron ulcers and erosions.伴有卡梅伦溃疡和糜烂的食管裂孔疝
Gastrointest Endosc Clin N Am. 1996 Oct;6(4):671-9.