Seid Amir Sultan, Mamo Eyouel Assefa
Division of Gastroenterology, Department of Internal Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Senay Medical Center, Ethiopia.
Ann Med Surg (Lond). 2022 Mar 4;75:103469. doi: 10.1016/j.amsu.2022.103469. eCollection 2022 Mar.
Cameron Lesions are linear breaks in the proximal gastric mucosa, mostly in association with hiatal hernia. The condition presents with chronic iron deficiency anemia and occasionally with obscure bleeding. Overt bleeding is very rare and has not been reported in sub- Saharan Africa context.
A 78 year old male patient, with an already diagnosed hiatal hernia and gouty arthritis, presented with massive upper GI bleeding requiring resuscitation and blood transfusion. The patient was taking indomethacin for a gout flare prior to the episode and clinical suspicion was a peptic ulcer disease as the culprit for the bleeding. Endoscopy was done and it showed two linear erosions with recent bleeding in the hernia sac. No other bleeding source was identified. The patient was treated with a Proton Pump Inhibitor (PPI).
Cameron lesions could present with massive bleeding and should be actively looked for in patients with hiatal hernia as they could be easily missed. Even with concurrent NSAID use, the condition could be a cause of major bleeding and careful evaluation is important. Management entails PPI therapy with occasional endoscopic intervention.
In the setting of hiatal hernia, Cameron lesions should be actively looked for in patients presenting with overt GI bleeding.
卡梅伦病变是近端胃黏膜的线性破损,大多与食管裂孔疝相关。该病症表现为慢性缺铁性贫血,偶尔伴有隐匿性出血。显性出血非常罕见,在撒哈拉以南非洲地区尚未见报道。
一名78岁男性患者,已确诊患有食管裂孔疝和痛风性关节炎,出现大量上消化道出血,需要进行复苏和输血治疗。该患者在此次发作前因痛风发作正在服用吲哚美辛,临床怀疑出血的罪魁祸首是消化性溃疡病。进行了内镜检查,结果显示疝囊内有两处近期出血的线性糜烂。未发现其他出血源。该患者接受了质子泵抑制剂(PPI)治疗。
卡梅伦病变可能表现为大量出血,对于患有食管裂孔疝的患者应积极排查,因为它们很容易被漏诊。即使同时使用非甾体抗炎药,该病症也可能是大出血的原因,进行仔细评估很重要。治疗方法包括PPI治疗,偶尔需要进行内镜干预。
在食管裂孔疝的情况下,对于出现显性胃肠道出血的患者应积极排查卡梅伦病变。